Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50037779
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195589(2-amino-1,5-dihydro-7-[[(2S,4R)-2-(hydroxymethyl)-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195587(CHEMBL218291 | CHEMBL1213652 | 1,4-DIDEOXY-4-AZA-1...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195593(2-amino-1,5-dihydro-7-[[(2S)-2-(hydroxymethyl)-1-p...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195597(2-amino-1,5-dihydro-7-[[N,N-bis-[2-(hydroxy)ethyl]...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195591(2-amino-1,5-dihydro-7-[[[2-(hydroxy)ethyl]amino]me...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195595(2-amino-1,5-dihydro-7-[[[N-[2-(hydroxy)ethyl]-N-me...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195588(2-amino-1,5-dihydro-7-[[N-[ethyl]-N-[2-(hydroxy)et...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195594(2-amino-1,5-dihydro-7-[[(2S)-2-(methoxymethyl)-1-p...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195590(2-amino-1,5-dihydro-7-[[(2S)-2-(aminomethyl)-1-pyr...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195596(2-amino-1,5-dihydro-7-[[(2R)-2-(hydroxymethyl)-1-p...)
Affinity DataIC50: 620nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195592(2-amino-1,5-dihydro-7-[[3-(hydroxymethyl)-1-piperi...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195589(2-amino-1,5-dihydro-7-[[(2S,4R)-2-(hydroxymethyl)-...)
Affinity DataKi:  1nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195587(CHEMBL218291 | CHEMBL1213652 | 1,4-DIDEOXY-4-AZA-1...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195593(2-amino-1,5-dihydro-7-[[(2S)-2-(hydroxymethyl)-1-p...)
Affinity DataKi:  2nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195597(2-amino-1,5-dihydro-7-[[N,N-bis-[2-(hydroxy)ethyl]...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195591(2-amino-1,5-dihydro-7-[[[2-(hydroxy)ethyl]amino]me...)
Affinity DataKi:  10.2nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195595(2-amino-1,5-dihydro-7-[[[N-[2-(hydroxy)ethyl]-N-me...)
Affinity DataKi:  30.6nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195588(2-amino-1,5-dihydro-7-[[N-[ethyl]-N-[2-(hydroxy)et...)
Affinity DataKi:  112nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195594(2-amino-1,5-dihydro-7-[[(2S)-2-(methoxymethyl)-1-p...)
Affinity DataKi:  306nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195590(2-amino-1,5-dihydro-7-[[(2S)-2-(aminomethyl)-1-pyr...)
Affinity DataKi:  306nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195596(2-amino-1,5-dihydro-7-[[(2R)-2-(hydroxymethyl)-1-p...)
Affinity DataKi:  316nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50195592(2-amino-1,5-dihydro-7-[[3-(hydroxymethyl)-1-piperi...)
Affinity DataKi:  2.04E+3nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed