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Found
33
Enz. Inhib. hit(s) with all data for entry = 50022543
Target
Mitogen-activated protein kinase 3
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 0.130nM
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Date in BDB:
10/13/2025
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Target
Vascular endothelial growth factor receptor 2
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 0.160nM
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Date in BDB:
10/13/2025
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Target
Mitogen-activated protein kinase 1
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 0.180nM
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Date in BDB:
10/13/2025
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Target
Vascular endothelial growth factor receptor 1
(Mouse)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 0.210nM
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Date in BDB:
10/13/2025
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Target
Vascular endothelial growth factor receptor 3
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 0.240nM
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Date in BDB:
10/13/2025
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Target
Epidermal growth factor receptor
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 1nM
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Date in BDB:
10/13/2025
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Target
Tyrosine-protein kinase JAK2
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 1nM
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Date in BDB:
10/13/2025
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Target
Insulin-like growth factor 1 receptor
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 1nM
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Date in BDB:
10/13/2025
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Target
Receptor tyrosine-protein kinase erbB-4
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 1nM
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Date in BDB:
10/13/2025
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Target
Focal adhesion kinase 1
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 1nM
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Date in BDB:
10/13/2025
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Target
Insulin receptor
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 1nM
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Date in BDB:
10/13/2025
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Target
Receptor tyrosine-protein kinase erbB-2
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 1nM
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Date in BDB:
10/13/2025
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Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 1nM
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Date in BDB:
10/13/2025
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Target
Fibroblast growth factor receptor 4
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
Copy SMILES
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Affinity Data
IC50: 1nM
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Date in BDB:
10/13/2025
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Target
Fibroblast growth factor receptor 3
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
Copy SMILES
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Affinity Data
IC50: 1nM
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Date in BDB:
10/13/2025
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Target
Mast/stem cell growth factor receptor Kit
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 1.60nM
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Date in BDB:
10/13/2025
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Target
Platelet-derived growth factor receptor beta
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 1.70nM
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Date in BDB:
10/13/2025
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Target
Vascular endothelial growth factor receptor 2
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 6.5nM
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Date in BDB:
10/13/2025
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Target
Vascular endothelial growth factor receptor 3
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
Copy SMILES
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Affinity Data
IC50: 15nM
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Date in BDB:
10/13/2025
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Target
Ephrin type-B receptor 2
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 24nM
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Date in BDB:
10/13/2025
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Target
Vascular endothelial growth factor receptor 1
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 30nM
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Date in BDB:
10/13/2025
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Target
Platelet-derived growth factor receptor alpha
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 40nM
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Date in BDB:
10/13/2025
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Target
Platelet-derived growth factor receptor beta
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 49nM
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Date in BDB:
10/13/2025
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Target
Mast/stem cell growth factor receptor Kit
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 78nM
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Date in BDB:
10/13/2025
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Target
Angiopoietin-1 receptor
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
Copy SMILES
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Affinity Data
IC50: 78nM
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Date in BDB:
10/13/2025
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Target
Fibroblast growth factor receptor 1
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
Copy SMILES
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Affinity Data
IC50: 299nM
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Date in BDB:
10/13/2025
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Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
Copy SMILES
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Affinity Data
IC50: 422nM
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Date in BDB:
10/13/2025
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Target
Ephrin type-B receptor 4
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
Copy SMILES
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Affinity Data
IC50: 480nM
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Date in BDB:
10/13/2025
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Target
Fibroblast growth factor receptor 1
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
Copy SMILES
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Affinity Data
IC50: 530nM
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Date in BDB:
10/13/2025
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Target
Hepatocyte growth factor receptor
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
Copy SMILES
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Affinity Data
IC50: 550nM
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Date in BDB:
10/13/2025
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Target
Tyrosine-protein kinase ABL1
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 620nM
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Date in BDB:
10/13/2025
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Target
Proto-oncogene tyrosine-protein kinase Src
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
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Affinity Data
IC50: 960nM
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Date in BDB:
10/13/2025
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Target
Hepatocyte growth factor receptor
(Human)
Kirin Brewery, Co., Ltd.
Curated by
ChEMBL
Ligand
BDBM50331095
(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
Copy SMILES
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IC50: 1.36E+3nM
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Date in BDB:
10/13/2025
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