Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 1582
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12340(3-{[(E)-({4-amino-6-[(4-fluoro-2-methyl-1H-indol-5...)
Affinity DataIC50: 11nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12336(6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-[...)
Affinity DataIC50: 24nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12338(6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-(...)
Affinity DataIC50: 33nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12334(6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-{...)
Affinity DataIC50: 39nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12324(5-[(1E)-(ethoxyimino)methyl]-6-[(4-fluoro-2-methyl...)
Affinity DataIC50: 42nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12325(6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-(...)
Affinity DataIC50: 43nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12339(2-{[(E)-({4-amino-6-[(4-fluoro-2-methyl-1H-indol-5...)
Affinity DataIC50: 44nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12328(6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-[...)
Affinity DataIC50: 52nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12327(6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-[...)
Affinity DataIC50: 52nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12337(6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-[...)
Affinity DataIC50: 62nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12331(6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-{...)
Affinity DataIC50: 93nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12335(5-[(1E)-{[3-(dimethylamino)propoxy]imino}methyl]-6...)
Affinity DataIC50: 101nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12326(5-[(1E)-(butoxyimino)methyl]-6-[(4-fluoro-2-methyl...)
Affinity DataIC50: 115nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12322(6-[(4-fluoro-1H-indol-5-yl)oxy]-5-[(1E)-(methoxyim...)
Affinity DataIC50: 117nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12323(6-[(6-fluoro-1H-indol-5-yl)oxy]-5-[(1E)-(methoxyim...)
Affinity DataIC50: 121nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12320(5-[(1E)-(methoxyimino)methyl]-6-[(2-methyl-1H-indo...)
Affinity DataIC50: 146nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12332(5-[(1E)-{[2-(dimethylamino)ethoxy]imino}methyl]-6-...)
Affinity DataIC50: 187nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12330(5-[(1E)-[(benzyloxy)imino]methyl]-6-[(4-fluoro-2-m...)
Affinity DataIC50: 201nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12333(6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-{...)
Affinity DataIC50: 214nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12318(6-(1H-indol-5-yloxy)-5-[(1E)-(methoxyimino)methyl]...)
Affinity DataIC50: 276nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12329(5-[(1E)-[(cyclohexylmethoxy)imino]methyl]-6-[(4-fl...)
Affinity DataIC50: 413nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12316(5-[(1E)-(methoxyimino)methyl]-6-(quinolin-6-yloxy)...)
Affinity DataIC50: 700nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12321(5-[(1E)-(methoxyimino)methyl]-6-[(3-methyl-1H-indo...)
Affinity DataIC50: 1.04E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12319(5-[(1E)-(methoxyimino)methyl]-6-[(1-methyl-1H-indo...)
Affinity DataIC50: 1.19E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12317(5-[(1E)-(methoxyimino)methyl]-6-(quinolin-7-yloxy)...)
Affinity DataIC50: 1.59E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed