Compile Data Set for Download or QSAR
Report error Found 147 Enz. Inhib. hit(s) with all data for entry = 50018351
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194684BDBM50194684(4-methyl-N-(2-methyl-3-4-methyl-N-(2-methyl-3-(2-(...)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194688BDBM50194688(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194668BDBM50194668(4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14949BDBM14949(3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194694BDBM50194694(N-(2,3-dihydro-1H-inden-4-yl)-4-methyl-3-(2-(methy...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194691BDBM50194691(N-(4-methyl-3-(2-(methylamino)quinazolin-6-yl)phen...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35317BDBM35317(CHEMBL212964 | 4-Methyl-3-(2-(methylamino)quinazol...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194670BDBM50194670(3-(2-aminoquinazolin-6-yl)-4-chloro-N-(3-(trifluor...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194686BDBM50194686(1-(2-(4-methyl-3-(2-(methylamino)quinazolin-6-yl)b...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194678BDBM50194678(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194681BDBM50194681(N-(4-chloro-3-(trifluoromethyl)phenyl)-4-methyl-3-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194671BDBM50194671(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194690BDBM50194690(2-fluoro-4-methyl-5-(2-(methylamino)quinazolin-6-y...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194683BDBM50194683(N-{2-[(N,N-DIETHYLGLYCYL)AMINO]-5-(TRIFLUOROMETHYL...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194675BDBM50194675(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194679BDBM50194679(3-(2-aminoquinazolin-6-yl)-4-methyl-N-(2-methyl-3-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194691BDBM50194691(N-(4-methyl-3-(2-(methylamino)quinazolin-6-yl)phen...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194700BDBM50194700(5-(2-aminoquinazolin-6-yl)-2-fluoro-4-methyl-N-(3-...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50194668BDBM50194668(4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...)
Affinity DataIC50: 1nMAssay Description:Inhibition of KDR by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194674BDBM50194674(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(4-(...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 35317BDBM35317(CHEMBL212964 | 4-Methyl-3-(2-(methylamino)quinazol...)
Affinity DataIC50: 1nMAssay Description:Inhibition of KDR by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194672BDBM50194672(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50194668BDBM50194668(4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Src by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194685BDBM50194685(N-(2-(3,3-dimethyl-2-oxoazetidin-1-yl)-5-(trifluor...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194675BDBM50194675(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194697BDBM50194697(4-methyl-N-(2-(3-methyl-2-oxoimidazolidin-1-yl)-5-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35317BDBM35317(CHEMBL212964 | 4-Methyl-3-(2-(methylamino)quinazol...)
Affinity DataIC50: 2nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14949BDBM14949(3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...)
Affinity DataIC50: 2nMAssay Description:Inhibition of KDR by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194688BDBM50194688(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194695BDBM50194695(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194689BDBM50194689(N-(4-chloro-2-methyl-3-(trifluoromethyl)phenyl)-4-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50194681BDBM50194681(N-(4-chloro-3-(trifluoromethyl)phenyl)-4-methyl-3-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of KDR by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194668BDBM50194668(4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...)
Affinity DataIC50: 3nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50194672BDBM50194672(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of KDR by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194697BDBM50194697(4-methyl-N-(2-(3-methyl-2-oxoimidazolidin-1-yl)-5-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50194691BDBM50194691(N-(4-methyl-3-(2-(methylamino)quinazolin-6-yl)phen...)
Affinity DataIC50: 5nMAssay Description:Inhibition of KDR by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194676BDBM50194676(1-(4-methyl-3-(2-(methylamino)quinazolin-6-yl)phen...)
Affinity DataIC50: 5nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50194688BDBM50194688(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of KDR by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194673BDBM50194673(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194698BDBM50194698(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14949BDBM14949(3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluor...)
Affinity DataIC50: 6nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194673BDBM50194673(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50194678BDBM50194678(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of KDR by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50194674BDBM50194674(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(4-(...)
Affinity DataIC50: 8nMAssay Description:Inhibition of KDR by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194676BDBM50194676(1-(4-methyl-3-(2-(methylamino)quinazolin-6-yl)phen...)
Affinity DataIC50: 8nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50194684BDBM50194684(4-methyl-N-(2-methyl-3-4-methyl-N-(2-methyl-3-(2-(...)
Affinity DataIC50: 8nMAssay Description:Inhibition of KDR by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194671BDBM50194671(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
Affinity DataIC50: 9nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194698BDBM50194698(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194687BDBM50194687(3-(2-(methylamino)quinazolin-6-yl)-N-(3-(trifluoro...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194681BDBM50194681(N-(4-chloro-3-(trifluoromethyl)phenyl)-4-methyl-3-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Displayed 1 to 50 (of 147 total ) | Next | Last >>
Jump to: