Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50018258
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193575(3-benzyl-1-methyl-6-(3-oxobutyl)-9-phenylpyrazolo[...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 20nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193586(7-benzyl-4-isopropyl-9-methyl-2-phenyl-7H-3,3a,5,7...)
Affinity DataIC50: 23nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193578(7-benzyl-4-ethyl-9-methyl-2-phenyl-7H-3,3a,5,7,8-p...)
Affinity DataIC50: 38nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Università

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 40nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193579(7-benzyl-9-methyl-2-phenyl-4-propyl-7H-3,3a,5,7,8-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193574(7-benzyl-2-furan-3-yl-4,9-dimethyl-7H-3,3a,5,7,8-p...)
Affinity DataIC50: 50nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193586(7-benzyl-4-isopropyl-9-methyl-2-phenyl-7H-3,3a,5,7...)
Affinity DataIC50: 62nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193577(3-benzyl-1-ethoxymethyl-6-methyl-9-phenylpyrazolo[...)
Affinity DataIC50: 71nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193585(methyl 3-benzyl-1-methyl-4-oxo-9-phenyl-3,4-dihydr...)
Affinity DataIC50: 79nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193576(5-(7-benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Affinity DataIC50: 95nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193583(3-benzyl-1-isopropyl-6-methyl-9-phenylpyrazolo[1',...)
Affinity DataIC50: 100nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193580(7-(3-methoxy-benzyl)-4,9-dimethyl-2-phenyl-7H-3,3a...)
Affinity DataIC50: 100nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193587(7-benzyl-4,9-dimethyl-2-thiophen-3-yl-7H-3,3a,5,7,...)
Affinity DataIC50: 140nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50165819(7-Benzyl-4,9-dimethyl-2-phenyl-7H-3,3a,5,7,8-penta...)
Affinity DataIC50: 160nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193584(3-benzyl-1-methyl-9-phenylpyrazolo[1',5':1,6]pyrim...)
Affinity DataIC50: 180nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193582(3-benzyl-1-ethyl-6-methyl-9-phenylpyrazolo[1',5':1...)
Affinity DataIC50: 220nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193581(4,9-dimethyl-2-phenyl-7-pyridin-4-ylmethyl-7H-3,3a...)
Affinity DataIC50: 240nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193569(7-benzyl-4,9-dimethyl-2-pyridin-3-yl-7H-3,3a,5,7,8...)
Affinity DataIC50: 280nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193574(7-benzyl-2-furan-3-yl-4,9-dimethyl-7H-3,3a,5,7,8-p...)
Affinity DataIC50: 330nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193577(3-benzyl-1-ethoxymethyl-6-methyl-9-phenylpyrazolo[...)
Affinity DataIC50: 330nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193571(3-benzyl-9-(4-chlorophenyl)-1,6-dimethylpyrazolo[1...)
Affinity DataIC50: 370nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193573(7-benzo[1,3]dioxol-5-ylmethyl-4,9-dimethyl-2-pheny...)
Affinity DataIC50: 390nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193569(7-benzyl-4,9-dimethyl-2-pyridin-3-yl-7H-3,3a,5,7,8...)
Affinity DataIC50: 470nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193578(7-benzyl-4-ethyl-9-methyl-2-phenyl-7H-3,3a,5,7,8-p...)
Affinity DataIC50: 550nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193579(7-benzyl-9-methyl-2-phenyl-4-propyl-7H-3,3a,5,7,8-...)
Affinity DataIC50: 610nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193584(3-benzyl-1-methyl-9-phenylpyrazolo[1',5':1,6]pyrim...)
Affinity DataIC50: 860nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193572(3-benzyl-1-[(dimethylamino)methyl]-6-methyl-9-phen...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193572(3-benzyl-1-[(dimethylamino)methyl]-6-methyl-9-phen...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193570(4,7,9-trimethyl-2-phenyl-7H-3,3a,5,7,8-pentaaza-cy...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193587(7-benzyl-4,9-dimethyl-2-thiophen-3-yl-7H-3,3a,5,7,...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193570(4,7,9-trimethyl-2-phenyl-7H-3,3a,5,7,8-pentaaza-cy...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50193571(3-benzyl-9-(4-chlorophenyl)-1,6-dimethylpyrazolo[1...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed