Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 2994
TargetMonoacylglycerol lipase ABHD6(Mouse)
The Scripps Research Institute

LigandPNGBDBM26736(N,N-dimethyl-5-[(4-phenylphenyl)methyl]-1H-1,2,3,4...)
Affinity DataIC50: 0.0900nMpH: 7.4 T: 2°CAssay Description:Serine hydrolase targets were recombinantly expressed in COS-7 cells by transient transfection. IC50 values were obtained by competitive ABPP with F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
The Scripps Research Institute

LigandPNGBDBM26736(N,N-dimethyl-5-[(4-phenylphenyl)methyl]-1H-1,2,3,4...)
Affinity DataIC50: 5.30nMpH: 7.4 T: 2°CAssay Description:Serine hydrolase targets were recombinantly expressed in COS-7 cells by transient transfection. IC50 values were obtained by competitive ABPP with F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetNeutral cholesterol ester hydrolase 1(Mouse)
The Scripps Research Institute

LigandPNGBDBM26736(N,N-dimethyl-5-[(4-phenylphenyl)methyl]-1H-1,2,3,4...)
Affinity DataIC50: 8.20nMpH: 7.4 T: 2°CAssay Description:Serine hydrolase targets were recombinantly expressed in COS-7 cells by transient transfection. IC50 values were obtained by competitive ABPP with F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
The Scripps Research Institute

LigandPNGBDBM26736(N,N-dimethyl-5-[(4-phenylphenyl)methyl]-1H-1,2,3,4...)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:Mouse brain membrane proteomes were preincubated with varying concentrations of inhibitors for 10 min prior to the addition of a rhodamine-tagged flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed