Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50018103
TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50191289(VUF-6884 | 7-chloro-11-(4-methylpiperazin-1-yl)-di...)
Affinity DataKd:  13nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor transfected in SK-N-MC cells at 10 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKd:  20.9nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor transfected in SK-N-MC cells at 300 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50191289(VUF-6884 | 7-chloro-11-(4-methylpiperazin-1-yl)-di...)
Affinity DataKd:  72nMAssay Description:Displacement of [3H]Histamine from human histamine H4 receptor transfected in SK-N-MC cells at 100 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKd:  14.5nMAssay Description:Displacement of [3H]Histamine from human histamine H4 receptor transfected in SK-N-MC cells at 100 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKd:  11.9nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor transfected in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50191289(VUF-6884 | 7-chloro-11-(4-methylpiperazin-1-yl)-di...)
Affinity DataKd:  22.2nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor transfected in SK-N-MC cells at 30 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50191289(VUF-6884 | 7-chloro-11-(4-methylpiperazin-1-yl)-di...)
Affinity DataKd:  10.7nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor transfected in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKd:  70.2nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor transfected in SK-N-MC cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)