Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50037763
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190017((4R,5R)-4-(2-fluorophenyl)-5-((S)-hydroxy(5-phenyl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190010((4R,5R)-4-(2-fluorophenyl)-5-((S)-hydroxy(5-(pyrid...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190020(4-(5-((S)-hydroxy((2R,3R)-1-methyl-5-oxo-3-phenylp...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190010((4R,5R)-4-(2-fluorophenyl)-5-((S)-hydroxy(5-(pyrid...)
Affinity DataIC50: 30nMAssay Description:Inhibition of estradiol to estrone conversion in MG63 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190030((4R,5R)-5-((S)-hydroxy(5-(phenylsulfonyl)thiophen-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190004((4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophen...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190004((4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophen...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190004((4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophen...)
Affinity DataIC50: 60nMAssay Description:Inhibition of estradiol to estrone conversion in MG63 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190015((4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophen...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190031((4R,5R)-5-((S)-hydroxy(5-(morpholinosulfonyl)thiop...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190011((4R,5R)-5-((S)-hydroxy(5-(pyridin-3-yl)thiophen-2-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of estradiol to estrone conversion in MG63 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190006((4R,5R)-5-((S)-(5-(4-fluorophenyl)thiophen-2-yl)(h...)
Affinity DataIC50: 100nMAssay Description:Inhibition of estradiol to estrone conversion in MG63 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190009((4R,5R)-5-((S)-hydroxy(5-phenylthiophen-2-yl)methy...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190028((4R,5R)-5-((S)-(5-(2-fluorophenyl)thiophen-2-yl)(h...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190035((4R,5R)-5-((S)-(5-(4-fluorophenyl)thiophen-2-yl)(h...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190006((4R,5R)-5-((S)-(5-(4-fluorophenyl)thiophen-2-yl)(h...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190006((4R,5R)-5-((S)-(5-(4-fluorophenyl)thiophen-2-yl)(h...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190036((4R,5R)-5-((S)-hydroxy(5-(pyridin-2-yl)thiophen-2-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190014((4R,5R)-5-((S)-(5-(3-(dimethylamino)phenyl)thiophe...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190008((4R,5R)-5-((S)-hydroxy(5-(phenylsulfonyl)thiophen-...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190008((4R,5R)-5-((S)-hydroxy(5-(phenylsulfonyl)thiophen-...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190023((4R,5R)-5-((S)-(5-(4-chlorophenylsulfonyl)thiophen...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190037((4R,5R)-5-((S)-hydroxy(5-(2-(trifluoromethyl)pheny...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190011((4R,5R)-5-((S)-hydroxy(5-(pyridin-3-yl)thiophen-2-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190011((4R,5R)-5-((S)-hydroxy(5-(pyridin-3-yl)thiophen-2-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190024((4R,5R)-5-((S)-hydroxy(5-methyl-3-phenylthiophen-2...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190034((4R,5R)-5-((S)-hydroxy(5-(phenylthio)thiophen-2-yl...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190025((4R,5R)-5-((S)-hydroxy(5-(3-methoxyphenyl)thiophen...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190026(4-(5-((S)-hydroxy((2R,3R)-1-methyl-5-oxo-3-phenylp...)
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190008((4R,5R)-5-((S)-hydroxy(5-(phenylsulfonyl)thiophen-...)
Affinity DataIC50: 480nMAssay Description:Inhibition of estradiol to estrone conversion in MG63 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190027((4R,5R)-4-(3-fluorophenyl)-5-((S)-(5-(4-fluorophen...)
Affinity DataIC50: 480nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190007((4R,5R)-5-((S)-hydroxy(5-(4-hydroxyphenyl)thiophen...)
Affinity DataIC50: 480nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190022((4R,5R)-5-((S)-hydroxy(4-phenylthiophen-2-yl)methy...)
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190018((4R,5R)-5-((S)-(5-(3-fluorophenyl)thiophen-2-yl)(h...)
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190029((4R,5R)-5-((S)-benzo[b]thiophen-2-yl(hydroxy)methy...)
Affinity DataIC50: 590nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190013((4R,5R)-4-(4-fluorophenyl)-5-((S)-hydroxy(5-phenyl...)
Affinity DataIC50: 760nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190021((4R,5R)-5-((S)-hydroxy(5-phenylthiophen-2-yl)methy...)
Affinity DataIC50: 880nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190005((4R,5R)-5-((S)-(5-benzoylthiophen-2-yl)(hydroxy)me...)
Affinity DataIC50: 950nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190032((4R,5R)-5-((S)-(5-(4-fluorobenzyl)thiophen-2-yl)(h...)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190016((4R,5R)-5-((S)-(5-(4-chlorophenyl)thiophen-2-yl)(h...)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190012(3-(5-((S)-hydroxy((2R,3R)-1-methyl-5-oxo-3-phenylp...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190033((4R,5R)-5-((S)-(5-(4-fluorophenyl)thiophen-2-yl)(h...)
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190019((4R,5R)-5-((S)-hydroxy(5-(4-(trifluoromethyl)pheny...)
Affinity DataIC50: 4.11E+3nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed