Compile Data Set for Download or QSAR
Report error Found 130 Enz. Inhib. hit(s) with all data for entry = 1994
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15956(N-[4-amino-5-cyano-6-(propan-2-yloxy)pyridin-2-yl]...)
Affinity DataIC50: 14nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15938(N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-acet...)
Affinity DataIC50: 26nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15938(N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-acet...)
Affinity DataIC50: 35nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15976(N-(4-amino-5-chloro-6-ethoxypyridin-2-yl)-2-(4-met...)
Affinity DataIC50: 36nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15939(N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-meth...)
Affinity DataIC50: 38nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15908(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-di...)
Affinity DataIC50: 45nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15956(N-[4-amino-5-cyano-6-(propan-2-yloxy)pyridin-2-yl]...)
Affinity DataIC50: 64nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15941(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-di...)
Affinity DataIC50: 69nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15952(1-[(4-Amino-5-cyano-6-ethoxypyridin-2-ylcarbamoyl)...)
Affinity DataIC50: 69nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15976(N-(4-amino-5-chloro-6-ethoxypyridin-2-yl)-2-(4-met...)
Affinity DataIC50: 70nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15962(N-[4-Amino-5-cyano-6-(2-hydroxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 74nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15940(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-brom...)
Affinity DataIC50: 77nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15953(1-[(4-Amino-5-cyano-6-ethoxypyridin-2ylcarbamoyl)m...)
Affinity DataIC50: 87nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15941(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-di...)
Affinity DataIC50: 100nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15963(N-[4-Amino-5-cyano-6-(2-methoxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 110nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15933(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2-meth...)
Affinity DataIC50: 120nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15953(1-[(4-Amino-5-cyano-6-ethoxypyridin-2ylcarbamoyl)m...)
Affinity DataIC50: 130nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15939(N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-meth...)
Affinity DataIC50: 150nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15948(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-[(2-hyd...)
Affinity DataIC50: 160nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15908(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-di...)
Affinity DataIC50: 160nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15940(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-brom...)
Affinity DataIC50: 160nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15935(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-meth...)
Affinity DataIC50: 180nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15952(1-[(4-Amino-5-cyano-6-ethoxypyridin-2-ylcarbamoyl)...)
Affinity DataIC50: 180nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15932(N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-meth...)
Affinity DataIC50: 190nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15934(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(3-meth...)
Affinity DataIC50: 210nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15962(N-[4-Amino-5-cyano-6-(2-hydroxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 240nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15933(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2-meth...)
Affinity DataIC50: 260nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15950(N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(morpho...)
Affinity DataIC50: 270nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15963(N-[4-Amino-5-cyano-6-(2-methoxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 270nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15935(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-meth...)
Affinity DataIC50: 274nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15928(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(3-chlo...)
Affinity DataIC50: 300nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15951(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-hydr...)
Affinity DataIC50: 300nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15955(N-[4-amino-5-cyano-6-(propan-2-yloxy)pyridin-2-yl]...)
Affinity DataIC50: 310nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15934(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(3-meth...)
Affinity DataIC50: 310nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15923(N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)pentanamid...)
Affinity DataIC50: 350nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15932(N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-meth...)
Affinity DataIC50: 360nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15930(N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2-meth...)
Affinity DataIC50: 400nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15964(N-[4-amino-5-cyano-6-(2-methanesulfonylethoxy)pyri...)
Affinity DataIC50: 400nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15931(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-m-tolyl...)
Affinity DataIC50: 420nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15955(N-[4-amino-5-cyano-6-(propan-2-yloxy)pyridin-2-yl]...)
Affinity DataIC50: 470nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15949(N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(piperi...)
Affinity DataIC50: 510nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15926(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-phenyla...)
Affinity DataIC50: 570nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15929(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-chlo...)
Affinity DataIC50: 580nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15929(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-chlo...)
Affinity DataIC50: 610nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15951(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-hydr...)
Affinity DataIC50: 640nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15923(N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)pentanamid...)
Affinity DataIC50: 690nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15930(N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2-meth...)
Affinity DataIC50: 740nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15948(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-[(2-hyd...)
Affinity DataIC50: 740nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15964(N-[4-amino-5-cyano-6-(2-methanesulfonylethoxy)pyri...)
Affinity DataIC50: 740nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15907(Aminopyridine-Based Inhibitor 6a | N-(4-Amino-5-cy...)
Affinity DataIC50: 750nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
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