Compile Data Set for Download or QSAR
Report error Found 100 Enz. Inhib. hit(s) with all data for entry = 50017845
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50: 40nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187340((6-Chloro-1H-indol-2-yl)-(5-methoxy-1H-indol-2-yl)...)
Affinity DataIC50: 55nMAssay Description:Inhibition of human PDGFR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187345((5-Hydroxy-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)...)
Affinity DataIC50: 60nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187345((5-Hydroxy-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50: 100nMAssay Description:Antiproliferative activity against mouse 32Dcl3 cell line expressing wild-type FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50: 100nMAssay Description:Antiproliferative activity against mouse 32Dcl3 cell line expressing FLT3-ITDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187369((5-Fluoro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50: 170nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50: 171nMAssay Description:Inhibition of human PDGFR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187340((6-Chloro-1H-indol-2-yl)-(5-methoxy-1H-indol-2-yl)...)
Affinity DataIC50: 200nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM6581(2-(1H-indol-2-ylcarbonyl)-1H-indol-5-ol | CHEMBL77...)
Affinity DataIC50: 200nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187357((4-Methyl-1H-indol-2-yl)-[5-(2-piperidin-1-yl-etho...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50: 300nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM6574(2-(1H-indol-2-ylcarbonyl)-6-methoxy-1H-indole | CH...)
Affinity DataIC50: 300nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM6573(CHEMBL7296 | (5-Methoxy-1H-2-indolyl)(1H-2-indolyl...)
Affinity DataIC50: 300nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187365((4-Fluoro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50: 340nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187348((5-Fluoro-1H-indol-2-yl)-(5-methoxy-1H-indol-2-yl)...)
Affinity DataIC50: 400nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187345((5-Hydroxy-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)...)
Affinity DataIC50: 458nMAssay Description:Inhibition of human PDGFR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50: 500nMAssay Description:Inhibition of DNA synthesis in IL3 dependent FDC-P1 cells expressing KIT V558D mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50: 500nMAssay Description:Inhibition of DNA synthesis in IL3 dependent FDC-P1 cells expressing wild-type KITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187356((5-Fluoro-1H-indol-2-yl)-[5-(2-piperidin-1-yl-etho...)
Affinity DataIC50: 500nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187345((5-Hydroxy-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)...)
Affinity DataIC50: 500nMAssay Description:Inhibition of DNA synthesis in IL3 dependent FDC-P1 cells expressing KIT V558D mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187345((5-Hydroxy-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)...)
Affinity DataIC50: 500nMAssay Description:Inhibition of DNA synthesis in IL3 dependent FDC-P1 cells expressing wild-type KITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187361((4-Chloro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50: 500nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187366((5-Methoxy-1H-indol-2-yl)-(6-methyl-1H-indol-2-yl)...)
Affinity DataIC50: 510nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187344((5-Hydroxy-1H-indol-2-yl)-(6-methoxy-1H-indol-2-yl...)
Affinity DataIC50: 530nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM6581(2-(1H-indol-2-ylcarbonyl)-1H-indol-5-ol | CHEMBL77...)
Affinity DataIC50: 570nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187367((5-Hydroxy-1H-indol-2-yl)-(6-methyl-1H-indol-2-yl)...)
Affinity DataIC50: 580nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187364((6-Fluoro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50: 590nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187365((4-Fluoro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50: 620nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187344((5-Hydroxy-1H-indol-2-yl)-(6-methoxy-1H-indol-2-yl...)
Affinity DataIC50: 650nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187373((5-Hydroxy-1H-indol-2-yl)-(4-methoxy-1H-indol-2-yl...)
Affinity DataIC50: 670nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187357((4-Methyl-1H-indol-2-yl)-[5-(2-piperidin-1-yl-etho...)
Affinity DataIC50: 700nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187369((5-Fluoro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50: 730nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187362((5-Hydroxy-1H-indol-2-yl)-(5-methyl-1H-indol-2-yl)...)
Affinity DataIC50: 740nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187349((5-fluoro-1H-indol-2-yl)-(1H-indol-2-yl)methanone ...)
Affinity DataIC50: 760nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187353((6-Fluoro-1H-indol-2-yl)-(5-methoxy-1H-indol-2-yl)...)
Affinity DataIC50: 840nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187348((5-Fluoro-1H-indol-2-yl)-(5-methoxy-1H-indol-2-yl)...)
Affinity DataIC50: 880nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM6574(2-(1H-indol-2-ylcarbonyl)-6-methoxy-1H-indole | CH...)
Affinity DataIC50: 890nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187361((4-Chloro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50: 920nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187373((5-Hydroxy-1H-indol-2-yl)-(4-methoxy-1H-indol-2-yl...)
Affinity DataIC50: 960nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187345((5-Hydroxy-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)...)
Affinity DataIC50: 960nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187371((6-Methoxy-1H-indol-2-yl)-[5-(2-piperidin-1-yl-eth...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187355(di(1H-indol-2-yl)methanone | CHEMBL207483)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187364((6-Fluoro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM33408(cid_2048 | CHEMBL7724 | AG1295)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187359((5-Fluoro-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187367((5-Hydroxy-1H-indol-2-yl)-(6-methyl-1H-indol-2-yl)...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187357((4-Methyl-1H-indol-2-yl)-[5-(2-piperidin-1-yl-etho...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human PDGFR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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