Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50017760
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186108(N-(((1S,3R)-3-(N-benzylpivalamido)cyclohexyl)methy...)
Affinity DataIC50: 8nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186103((R)-1-((3-(3-chlorobenzyl)-3-(2,2,2-trichloroaceta...)
Affinity DataIC50: 10nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186108(N-(((1S,3R)-3-(N-benzylpivalamido)cyclohexyl)methy...)
Affinity DataIC50: 10nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186102(N-((3-(N-(3-nitrobenzyl)-2,2,2-trichloroacetamido)...)
Affinity DataIC50: 14nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186113((R)-1-((3-benzyl-3-(2,2,2-trichloroacetamido)cyclo...)
Affinity DataIC50: 20nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186105(rac-N-((3-(N-(3-chlorobenzyl)-2,2,2-trichloroaceta...)
Affinity DataIC50: 21nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186116(rac-1-((3-(N-benzylpivalamido)cyclohexyl)methyl)-3...)
Affinity DataIC50: 21nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptor at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186111(rac-N-((3-(N-benzylpivalamido)cyclohexyl)methyl)-4...)
Affinity DataIC50: 24nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186109(rac-N-((3-(N-benzyl-2,2,2-trichloroacetamido)cyclo...)
Affinity DataIC50: 27nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186111(rac-N-((3-(N-benzylpivalamido)cyclohexyl)methyl)-4...)
Affinity DataIC50: 29nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186106(rac-1-((3-(N-(3-nitrobenzyl)-2,2,2-trichloroacetam...)
Affinity DataIC50: 35nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186110(rac-N-((3-(N-(3-chlorobenzyl)-2,2,2-trichloroaceta...)
Affinity DataIC50: 36nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186102(N-((3-(N-(3-nitrobenzyl)-2,2,2-trichloroacetamido)...)
Affinity DataIC50: 52nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186110(rac-N-((3-(N-(3-chlorobenzyl)-2,2,2-trichloroaceta...)
Affinity DataIC50: 58nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186109(rac-N-((3-(N-benzyl-2,2,2-trichloroacetamido)cyclo...)
Affinity DataIC50: 58nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186105(rac-N-((3-(N-(3-chlorobenzyl)-2,2,2-trichloroaceta...)
Affinity DataIC50: 63nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186112(N-(((1R,3S)-3-(N-benzylpivalamido)cyclohexyl)methy...)
Affinity DataIC50: 72nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186102(N-((3-(N-(3-nitrobenzyl)-2,2,2-trichloroacetamido)...)
Affinity DataIC50: 72nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186105(rac-N-((3-(N-(3-chlorobenzyl)-2,2,2-trichloroaceta...)
Affinity DataIC50: 228nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186110(rac-N-((3-(N-(3-chlorobenzyl)-2,2,2-trichloroaceta...)
Affinity DataIC50: 267nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186108(N-(((1S,3R)-3-(N-benzylpivalamido)cyclohexyl)methy...)
Affinity DataIC50: 338nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186112(N-(((1R,3S)-3-(N-benzylpivalamido)cyclohexyl)methy...)
Affinity DataIC50: 638nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186101(rac-1-((-3-(N-(3-chlorobenzyl)-3-methoxybenzamido)...)
Affinity DataIC50: 650nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186114(rac-1-((3-(N-benzylfuran-2-carboxamido)cyclohexyl)...)
Affinity DataIC50: 656nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186117(rac-1-((3-(N-benzyl-3-phenylpropanamido)cyclohexyl...)
Affinity DataIC50: 730nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186107(rac-1-((3-(N-benzylpivalamido)cyclohexyl)methyl)-3...)
Affinity DataIC50: 772nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186115(rac-1-((3-(N-benzyl-2,2,2-trichloroacetamido)cyclo...)
Affinity DataIC50: 957nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186111(rac-N-((3-(N-benzylpivalamido)cyclohexyl)methyl)-4...)
Affinity DataIC50: 990nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186104(rac-1-((3-(N-benzyl-3-nitrobenzamido)cyclohexyl)me...)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186112(N-(((1R,3S)-3-(N-benzylpivalamido)cyclohexyl)methy...)
Affinity DataIC50: 2.48E+3nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed