Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50017742
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185979(1-acetyl-N-{3-[4-(4-carbamoylbenzyl)piperidin-1-yl...)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185967(N-(3-(4-(4-(methylsulfonyl)benzyl)piperidin-1-yl)p...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185972(N-(3-(4-(4-fluorobenzyl)piperidin-1-yl)propyl)-1-a...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185973(N-{3-[4-(4-cyanobenzyl)piperidin-1-yl]propyl}-N-(3...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185963(1-acetyl-N-(3,4-dichlorophenyl)-N-(3-{4-[(4-fluoro...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185973(N-{3-[4-(4-cyanobenzyl)piperidin-1-yl]propyl}-N-(3...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185963(1-acetyl-N-(3,4-dichlorophenyl)-N-(3-{4-[(4-fluoro...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185964(N-{3-[4-(3-carbamoylbenzyl)piperidin-1-yl]propyl}-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185961(N-(3-(4-(4-fluorobenzyl)piperidin-1-yl)propyl)-N-(...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185978(1-acetyl-N-{3-[4-(4-carbamoylbenzyl)piperidin-1-yl...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185967(N-(3-(4-(4-(methylsulfonyl)benzyl)piperidin-1-yl)p...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185975(CHEMBL207654 | 1-acetyl-N-(3,4-dichlorophenyl)-N-(...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185964(N-{3-[4-(3-carbamoylbenzyl)piperidin-1-yl]propyl}-...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185968(1-acetyl-N-(3,4-dichlorophenyl)-N-(3-{4-[(4-fluoro...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185972(N-(3-(4-(4-fluorobenzyl)piperidin-1-yl)propyl)-1-a...)
Affinity DataIC50: 3nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185975(CHEMBL207654 | 1-acetyl-N-(3,4-dichlorophenyl)-N-(...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185961(N-(3-(4-(4-fluorobenzyl)piperidin-1-yl)propyl)-N-(...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185979(1-acetyl-N-{3-[4-(4-carbamoylbenzyl)piperidin-1-yl...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185978(1-acetyl-N-{3-[4-(4-carbamoylbenzyl)piperidin-1-yl...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185968(1-acetyl-N-(3,4-dichlorophenyl)-N-(3-{4-[(4-fluoro...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185971(N-(3,4-dichlorophenyl)-N-[3-(4-{[(4-fluorophenyl)s...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185971(N-(3,4-dichlorophenyl)-N-[3-(4-{[(4-fluorophenyl)s...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185970(methyl 4-({1-[3-((3,4-Dichlorophenyl){[1-(methylsu...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185969(N-(3,4-dichlorophenyl)-N-(3-{4-[4-(methylcarbamoyl...)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185980(N-{3-[4-(4-carbamoylbenzyl)piperidin-1-yl]propyl}-...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185966(N-{3-[4-(2-carbamoylbenzyl)piperidin-1-yl]propyl}-...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185970(methyl 4-({1-[3-((3,4-Dichlorophenyl){[1-(methylsu...)
Affinity DataIC50: 7nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185976(N-(3,4-dichlorophenyl)-N-(3-{4-[4-(dimethylcarbamo...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185980(N-{3-[4-(4-carbamoylbenzyl)piperidin-1-yl]propyl}-...)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185969(N-(3,4-dichlorophenyl)-N-(3-{4-[4-(methylcarbamoyl...)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185974(N-(3-{4-[4-(tert-butylcarbamoyl)benzyl]piperidin-1...)
Affinity DataIC50: 11nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185966(N-{3-[4-(2-carbamoylbenzyl)piperidin-1-yl]propyl}-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185974(N-(3-{4-[4-(tert-butylcarbamoyl)benzyl]piperidin-1...)
Affinity DataIC50: 12nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185960(1-acetyl-N-(3-(4-benzylpiperidin-1-yl)propyl)-N-ph...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185976(N-(3,4-dichlorophenyl)-N-(3-{4-[4-(dimethylcarbamo...)
Affinity DataIC50: 19nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185965(1-acetyl-N-(3,4-dichlorophenyl)-N-{3-[4-(4-fluoroa...)
Affinity DataIC50: 20nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185965(1-acetyl-N-(3,4-dichlorophenyl)-N-{3-[4-(4-fluoroa...)
Affinity DataIC50: 26nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185977(4-({1-[3-((3,4-dichlorophenyl){[1-(methylsulfonyl)...)
Affinity DataIC50: 44nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185977(4-({1-[3-((3,4-dichlorophenyl){[1-(methylsulfonyl)...)
Affinity DataIC50: 66nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185960(1-acetyl-N-(3-(4-benzylpiperidin-1-yl)propyl)-N-ph...)
Affinity DataIC50: 72nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185962(N-(3,4-dichlorophenyl)-N-(3-{4-[(4-fluorobenzoyl)a...)
Affinity DataIC50: 730nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed