Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50017721
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185681((R)-N-ethyl-N-(1-(3-(3-fluorophenyl)-3-(4-(methyls...)
Affinity DataIC50: 0.220nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185666((R)-N-(1-(3-(3,5-difluorophenyl)-3-(4-(methylsulfo...)
Affinity DataIC50: 0.320nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185673((S)-N-ethyl-2-(4-(methylsulfonyl)phenyl)-N-(1-(3-(...)
Affinity DataIC50: 0.760nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185670((R)-N-(1-(3-(3-chlorophenyl)-3-(4-(methylsulfonyl)...)
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185667((R)-N-(1-(3-(3-chloro-5-fluorophenyl)-3-(4-(methyl...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50173389(N-ethyl-2-(4-(methylsulfonyl)phenyl)-N-(1-(3-(4-(m...)
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185668((R)-N-ethyl-2-(4-(methylsulfonyl)phenyl)-N-(1-(3-(...)
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185676((R)-N-(1-(3-(2,3-difluorophenyl)-3-(4-(methylsulfo...)
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185672((R)-N-(1-(3-(3,4-difluorophenyl)-3-(4-(methylsulfo...)
Affinity DataIC50: 21nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185674((R)-N-ethyl-2-(4-(methylsulfonyl)phenyl)-N-(1-(3-(...)
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185669((R)-N-ethyl-N-(1-(3-(3-methoxyphenyl)-3-(4-(methyl...)
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185683((R)-N-(1-(3-(2,5-difluorophenyl)-3-(4-(methylsulfo...)
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185680((S)-N-(1-(3-(3,5-difluorophenyl)-3-(4-(methylsulfo...)
Affinity DataIC50: 40nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185677((S)-N-ethyl-N-(1-(3-(4-fluorophenyl)-3-(4-(methyls...)
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185678((R)-N-(1-(3-(3-cyanophenyl)-3-(4-(methylsulfonyl)p...)
Affinity DataIC50: 56nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185675((R)-N-ethyl-N-(1-(3-(3-isopropylphenyl)-3-(4-(meth...)
Affinity DataIC50: 110nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185682((S)-N-ethyl-N-(1-(3-(4-methoxyphenyl)-3-(4-(methyl...)
Affinity DataIC50: 132nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185679((R)-N-(1-(3-(3-tert-butylphenyl)-3-(4-(methylsulfo...)
Affinity DataIC50: 500nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185671((R)-N-(1-(3-(2,6-difluorophenyl)-3-(4-(methylsulfo...)
Affinity DataIC50: 560nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50173399(N-(1-(3,3-bis(4-fluorophenyl)propyl)piperidin-4-yl...)
Affinity DataIC50: 780nMAssay Description:Displacement of [125I]MIP-1-alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185666((R)-N-(1-(3-(3,5-difluorophenyl)-3-(4-(methylsulfo...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50185666((R)-N-(1-(3-(3,5-difluorophenyl)-3-(4-(methylsulfo...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185666((R)-N-(1-(3-(3,5-difluorophenyl)-3-(4-(methylsulfo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of P450 1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185666((R)-N-(1-(3-(3,5-difluorophenyl)-3-(4-(methylsulfo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185666((R)-N-(1-(3-(3,5-difluorophenyl)-3-(4-(methylsulfo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of P450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185666((R)-N-(1-(3-(3,5-difluorophenyl)-3-(4-(methylsulfo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of P450 2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed