Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50017649
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162116(2-(4-(benzyloxy)phenyl)-N-(1-(2-(pyrrolidin-1-yl)e...)
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50171590(N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-5...)
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173460(4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...)
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50185040(N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6...)
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50185041(N-(4-phenoxyphenyl)-N'-[1-(2-azepan-1-yl-ethyl)-1H...)
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50185044(N-(4-phenoxyphenyl)-N'-[1-(2-piperidin-1-ylethyl)-...)
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50185042(N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7...)
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50185046((1-benzo{1,3}dioxol-5-ylmethylpiperidin-4-yl)(6-me...)
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50167567(1-(4-Phenoxy-phenyl)-3-[1-(2-pyrrolidin-1-yl-ethyl...)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174895((1-benzo{1,3}dioxol-5-ylmethyl-piperidin-4-yl)(5-c...)
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162120(2-(4-(benzyloxy)phenyl)-N-(1-(2-(pyrrolidin-1-yl)e...)
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50185038(N-(4-phenoxyphenyl)-N'-[2-(2-pyrrolidin-1-ylethyl)...)
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50185045(N-{2-[2-(3-(S)-hydroxypyrrolidin-1-yl)ethyl]-2H-in...)
Affinity DataIC50: 57nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50185043(2-(4-phenoxyphenyl)-N-[1-(2-pyrrolidin-1-ylethyl)-...)
Affinity DataIC50: 78nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162115(2-(4-Benzyloxy-phenyl)-N-[1-(2-pyrrolidin-1-yl-eth...)
Affinity DataIC50: 558nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50185039(2-(4-Methoxyphenyl)-N-[1-(2-pyrrolidin-1-yl-ethyl)...)
Affinity DataIC50: 3.63E+3nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed