Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50017629
LigandPNGBDBM50184737(N-(4-(trifluoromethyl)phenyl)-4-(3-(trifluoromethy...)
Affinity DataIC50: 3nMpH: 5.5Assay Description:Inhibition of acidic pH 5.5-stimulated current in CHO cells expressing human TRPV1 receptor by patch clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184729(2-(4-(trifluoromethyl)phenyl)-6-(3-(trifluoromethy...)
Affinity DataIC50: 4nMpH: 5.5Assay Description:Inhibition of acidic pH 5.5-stimulated current in CHO cells expressing human TRPV1 receptor by patch clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184737(N-(4-(trifluoromethyl)phenyl)-4-(3-(trifluoromethy...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184738(2-(4-(trifluoromethyl)phenyl)-6-(3-(trifluoromethy...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184730(4-(trifluoromethyl)-N-(4-(3-(trifluoromethyl)pyrid...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184730(4-(trifluoromethyl)-N-(4-(3-(trifluoromethyl)pyrid...)
Affinity DataIC50: 33nMpH: 5.5Assay Description:Inhibition of acidic pH 5.5-stimulated current in CHO cells expressing human TRPV1 receptor by patch clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184729(2-(4-(trifluoromethyl)phenyl)-6-(3-(trifluoromethy...)
Affinity DataIC50: 35nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184745(N-(4-(3-methylpyridin-2-yl)phenyl)-4-(trifluoromet...)
Affinity DataIC50: 160nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184731(6-(2-methoxyphenyl)-2-(4-(trifluoromethyl)phenyl)-...)
Affinity DataIC50: 170nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184735(2-p-tolyl-6-(3-(trifluoromethyl)pyridin-2-yl)-1H-b...)
Affinity DataIC50: 170nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184740(6-(3-methylpyridin-2-yl)-2-(4-(trifluoromethyl)phe...)
Affinity DataIC50: 180nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184729(2-(4-(trifluoromethyl)phenyl)-6-(3-(trifluoromethy...)
Affinity DataIC50: 220nMAssay Description:Activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing rat TRPV1 assessed by patch clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184729(2-(4-(trifluoromethyl)phenyl)-6-(3-(trifluoromethy...)
Affinity DataIC50: 220nMAssay Description:Activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing rat TRPV1 assessed by patch clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184742(2-(4-tert-butylphenyl)-6-(3-(trifluoromethyl)pyrid...)
Affinity DataIC50: 224nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184734(6-(3-methylpyridin-2-yl)-2-(4-(trifluoromethyl)phe...)
Affinity DataIC50: 270nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184739(2-(4-(trifluoromethyl)phenyl)-6-(3-(trifluoromethy...)
Affinity DataIC50: 290nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184741(2-(4-fluorophenyl)-6-(3-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 320nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184747(2-(4-(trifluoromethyl)phenyl)-1,2-dihydroindazol-3...)
Affinity DataIC50: 340nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184743(2-(4-(trifluoromethyl)phenyl)-5-(3-(trifluoromethy...)
Affinity DataIC50: 370nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184746(4-tert-butyl-N-(4-(3-(trifluoromethyl)pyridin-2-yl...)
Affinity DataIC50: 470nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184733(N-(4-(3-methylpyridin-2-yl)phenyl)-3-(trifluoromet...)
Affinity DataIC50: 640nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184732(4-methyl-N-(4-(3-(trifluoromethyl)pyridin-2-yl)phe...)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184744(N-(4-(pyridin-2-yl)phenyl)-4-(trifluoromethyl)benz...)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50184736(N-(4-(3-(trifluoromethyl)pyridin-2-yl)phenyl)benza...)
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed