Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50038603
TargetAlpha-2A adrenergic receptor(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50013515(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
Affinity DataEC50:  8.5nMAssay Description:Displacement of [3H]MK912 from human recombinant adrenergic alpha2A receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50259677(escholtzine | CHEMBL481839)
Affinity DataEC50:  1.10E+4nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50250422(N-methyllaurotetanine | (+)-N-methyl-laurotetanine...)
Affinity DataEC50:  160nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50259678(caryachine | CHEMBL480663)
Affinity DataEC50:  9.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50377937(PROTOPINE)
Affinity DataEC50: >1.00E+5nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataEC50: >1.00E+5nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50377936(CALIFORNIDINE)
Affinity DataEC50: >1.00E+5nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50259674((S)-3-amino-4-((S)-1-((R)-1-((S)-1-((R)-1-((R)-1-(...)
Affinity DataEC50:  78.1nMAssay Description:Displacement of [3H]SR48968 from human recombinant NK2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50140771(L-703606 | (cis)-N-(2-iodobenzyl)-2-benzhydrylquin...)
Affinity DataEC50:  24.4nMAssay Description:Displacement of [3H]SR140333 from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM78940(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Affinity DataEC50:  0.600nMAssay Description:Displacement of [3H]lysergic acid from human recombinant 5HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM30704(METERGOLINE | (phenylmethyl) N-[[(6aR,9S,10aR)-4,7...)
Affinity DataEC50:  7.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM22567(CHEMBL511 | PYRILAMINE | 3H]pyrilamine | N-[2-(dim...)
Affinity DataEC50:  2.60nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataEC50:  0.0930nMAssay Description:Displacement of [125I]CCK-8 from CCK2 receptor in human FGS7 Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM21281(WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...)
Affinity DataEC50:  37.6nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB1 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50246936(S-(-)-propanolol | (-)-(S)-Propranolol | [2-Hydrox...)
Affinity DataEC50:  1.80nMAssay Description:Displacement of [125I]cyanopindolol from human recombinant adrenergic beta-1 receptor expressed in Rex16 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50118810(CHEMBL139000 | N6-[(R)-1-Methyl-2-phenylethyl]ado ...)
Affinity DataEC50:  1.20E+3nMAssay Description:Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50259677(escholtzine | CHEMBL481839)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50217942(3-Rhamnoglucosylquercetin | cid_5280805 | CHEMBL22...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50377936(CALIFORNIDINE)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50377937(PROTOPINE)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50250422(N-methyllaurotetanine | (+)-N-methyl-laurotetanine...)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50259677(escholtzine | CHEMBL481839)
Affinity DataKi:  6.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed