Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 1062
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

LigandPNGBDBM8540(4-[(1E)-{2-[3-(3-methoxyphenyl)-1H-pyrazolo[4,3-d]...)
Affinity DataIC50: 5.01nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

LigandPNGBDBM8536(4-[(1E)-{2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]p...)
Affinity DataIC50: 5.01nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

LigandPNGBDBM8535(4-[(1E)-{2-[1-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50: 6.30nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

LigandPNGBDBM8538(4-[(1E)-{2-[7-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50: 31.6nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

LigandPNGBDBM8537(4-[(1E)-{2-[7-(3-methoxyphenyl)-5-methyl-5H-pyrrol...)
Affinity DataIC50: 501nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

LigandPNGBDBM8539(9-(3-methoxyphenyl)-6-[(2E)-2-(pyridin-4-ylmethyli...)
Affinity DataIC50: 631nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2006
Entry Details Article
PubMed