Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 2748
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24127(CHEMBL205786 | (4R)-4-(3-hydroxyphenyl)-N,N,7,8-te...)
Affinity DataIC50: 104nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24128(CHEMBL380367 | 4-(3-hydroxyphenyl)-N,N,7,8-tetrame...)
Affinity DataIC50: 306nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24136(4-(3-hydroxyphenyl)-7-iodo-N,N-dimethyl-1,2,3,4-te...)
Affinity DataIC50: 317nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24143(8-ethyl-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-t...)
Affinity DataIC50: 344nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24147(6-(3-hydroxyphenyl)-N,N-dimethyl-4-azatricyclo[8.4...)
Affinity DataIC50: 477nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24137(4-(3-hydroxyphenyl)-N,N,7-trimethyl-1,2,3,4-tetrah...)
Affinity DataIC50: 595nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24138(4-(3-hydroxyphenyl)-7-methoxy-N,N-dimethyl-1,2,3,4...)
Affinity DataIC50: 617nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24148(10-(3-hydroxyphenyl)-N,N-dimethyl-3-oxa-12-azatric...)
Affinity DataIC50: 639nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24135(CHEMBL438800 | 7-bromo-4-(3-hydroxyphenyl)-N,N-dim...)
Affinity DataIC50: 808nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24146(7,8-dichloro-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,...)
Affinity DataIC50: 1.27E+3nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24144(4-(3-hydroxyphenyl)-8-methoxy-N,N-dimethyl-1,2,3,4...)
Affinity DataIC50: 1.78E+3nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24110(2-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...)
Affinity DataIC50: 2.27E+3nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24134(7-chloro-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-...)
Affinity DataIC50: 2.49E+3nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24123(N,N,7,8-tetramethyl-4-phenyl-1,2,3,4-tetrahydroiso...)
Affinity DataIC50: 2.75E+3nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24111(3-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...)
Affinity DataIC50: 3.06E+3nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24131(4-(3-chlorophenyl)-N,N,7,8-tetramethyl-1,2,3,4-tet...)
Affinity DataIC50: 3.48E+3nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24112(4-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...)
Affinity DataIC50: 4.65E+3nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24142(4-(3-hydroxyphenyl)-N,N,8-trimethyl-1,2,3,4-tetrah...)
Affinity DataIC50: 4.71E+3nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24115([4-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoqui...)
Affinity DataIC50: 5.36E+3nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24126(N-[3-(dimethylamino)propyl]-N,7,8-trimethyl-4-phen...)
Affinity DataIC50: 5.44E+3nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24105(CHEMBL208145 | 7,8-dimethyl-4-phenyl-1,2,3,4-tetra...)
Affinity DataIC50: 8.33E+3nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24114([3-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoqui...)
Affinity DataIC50: 8.88E+3nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24108(7,8-dimethyl-4-phenyl-2-(propan-2-yl)-1,2,3,4-tetr...)
Affinity DataIC50: 1.10E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24125(7,8-dimethyl-4-phenyl-2-(piperidin-1-ylcarbonyl)-1...)
Affinity DataIC50: 1.28E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24145(4-(3-hydroxyphenyl)-7,8-dimethoxy-N,N-dimethyl-1,2...)
Affinity DataIC50: 1.28E+4nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24130(N,N,7,8-tetramethyl-4-[3-(trifluoromethyl)phenyl]-...)
Affinity DataIC50: 1.32E+4nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24119(methyl 7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroiso...)
Affinity DataIC50: 1.44E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24117(2-benzoyl-7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydro...)
Affinity DataIC50: 1.64E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24116(1-(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...)
Affinity DataIC50: 1.79E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24106(2,7,8-trimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...)
Affinity DataIC50: 1.84E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24124(4-[(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoqui...)
Affinity DataIC50: 2.23E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24113(7,8-dimethyl-4-phenyl-2-[2-(1H-pyrrol-1-yl)ethyl]-...)
Affinity DataIC50: 2.50E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24141(8-bromo-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-t...)
Affinity DataIC50: 2.50E+4nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24140(8-chloro-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-...)
Affinity DataIC50: 2.50E+4nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24139(8-fluoro-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-...)
Affinity DataIC50: 2.50E+4nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24109(7,8-dimethyl-4-phenyl-2-(2-phenylethyl)-1,2,3,4-te...)
Affinity DataIC50: 2.50E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24118(2-methanesulfonyl-7,8-dimethyl-4-phenyl-1,2,3,4-te...)
Affinity DataIC50: 2.50E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24120(ethyl 7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoq...)
Affinity DataIC50: 2.50E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24133(7-fluoro-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-...)
Affinity DataIC50: 2.50E+4nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24132(4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-tetrahydr...)
Affinity DataIC50: 2.50E+4nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24121(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquinoli...)
Affinity DataIC50: 2.50E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24129(4-(4-hydroxyphenyl)-N,N,7,8-tetramethyl-1,2,3,4-te...)
Affinity DataIC50: 2.50E+4nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24122(N,7,8-trimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...)
Affinity DataIC50: 2.50E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Bristol-Myers Squibb

LigandPNGBDBM24107(CHEMBL207973 | 2-ethyl-7,8-dimethyl-4-phenyl-1,2,3...)
Affinity DataIC50: 2.52E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed