Compile Data Set for Download or QSAR
Report error Found 59 Enz. Inhib. hit(s) with all data for entry = 50017432
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182113(6-chloro-1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(...)
Affinity DataIC50: 13nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182103(6-chloro-4-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(...)
Affinity DataIC50: 16nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182108(1-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 18nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182117(6-chloro-1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(...)
Affinity DataIC50: 18nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182109(1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Affinity DataIC50: 23nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182110(4-(1-(3-(5-(methylsulfonyl)-3-(4-(trifluoromethyl)...)
Affinity DataIC50: 23nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182092(4-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Affinity DataIC50: 28nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182101(1-[4-(6-Chloro-2,2-dioxo-3,4-dihydro-2H-2lambda*6*...)
Affinity DataIC50: 30nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182118(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 32nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182100(1-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 33nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182099(1-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 33nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182097(1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Affinity DataIC50: 48nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182107(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 48nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182105(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 60nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182095(1-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 65nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182104(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 68nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182089(1-[3-(4-Bromo-phenyl)-5-methanesulfonyl-4,5,6,7-te...)
Affinity DataIC50: 75nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182098(4-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Affinity DataIC50: 80nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182093(1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Affinity DataIC50: 88nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182102(4-(1-(3-(5-acetyl-3-(4-(trifluoromethyl)phenyl)-4,...)
Affinity DataIC50: 100nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182087(4-(1-(3-(5-acetyl-3-(4-(trifluoromethyl)phenyl)-4,...)
Affinity DataIC50: 120nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182091(6-chloro-4-(1-(3-(5-(methylsulfonyl)-3-(4-(trifluo...)
Affinity DataIC50: 130nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182114(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 130nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182116(1-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 133nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182094(5-methyl-4-(1-(3-(5-(methylsulfonyl)-3-(4-(trifluo...)
Affinity DataIC50: 145nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182115(1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Affinity DataIC50: 163nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182106(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 170nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182120(1-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,6,7-te...)
Affinity DataIC50: 322nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182092(4-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Affinity DataIC50: 410nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182108(1-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 750nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182102(4-(1-(3-(5-acetyl-3-(4-(trifluoromethyl)phenyl)-4,...)
Affinity DataIC50: 810nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182090(tert-butyl 1-(2-hydroxy-3-(4-(3-oxo-2,3-dihydroben...)
Affinity DataIC50: 826nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182104(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 900nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182112(tert-butyl 1-(3-(4-(3-oxo-2,3-dihydrobenzo[b][1,4]...)
Affinity DataIC50: 900nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182115(1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Affinity DataIC50: 930nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182110(4-(1-(3-(5-(methylsulfonyl)-3-(4-(trifluoromethyl)...)
Affinity DataIC50: 950nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182113(6-chloro-1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(...)
Affinity DataIC50: 980nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182087(4-(1-(3-(5-acetyl-3-(4-(trifluoromethyl)phenyl)-4,...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182095(1-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182103(6-chloro-4-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182101(1-[4-(6-Chloro-2,2-dioxo-3,4-dihydro-2H-2lambda*6*...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182098(4-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182097(1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182093(1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182099(1-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182105(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182106(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182088(1-(5-(methylsulfonyl)-3-(4-(trifluoromethyl)phenyl...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182111(1-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,6,7-te...)
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182119(4-(1-(3-(3-(4-(trifluoromethyl)phenyl)-4,5,6,7-tet...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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