Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50037651
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180020(4-oxo-1-pentyl-1,4-dihydro-quinoline-3-carboxylic ...)
Affinity DataEC50:  14.1nMAssay Description:Effect on [35S]GTP-gamma-S binding to human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM21281(WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...)
Affinity DataEC50:  24.6nMAssay Description:Effect on [35S]GTP-gamma-S binding to human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180021((R)-N3-(1-phenylethyl)-4-oxo-1-pentyl-1,4-dihydroq...)
Affinity DataEC50:  16.8nMAssay Description:Effect on [35S]GTP-gamma-S binding to human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataEC50:  2.10nMAssay Description:Effect on [35S]GTP-gamma-S binding to human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataEC50:  4.10nMAssay Description:Effect on [35S]GTP-gamma-S binding to human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180036(CHEMBL371214 | (6aR,10aR)-3-(1,1-dimethylbutyl)-6a...)
Affinity DataEC50:  146nMAssay Description:Effect on [35S]GTP-gamma-S binding to human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  6.10nMAssay Description:Effect on [35S]GTP-gamma-S binding to human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180026(N3-(2-adamantyl)-4-oxo-1-pentyl-1,4-dihydroquinoli...)
Affinity DataEC50:  24.8nMAssay Description:Effect on [35S]GTP-gamma-S binding to human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180028((RS)-N3-(1-(1,2,3,4-tetrahydronaphthyl))-4-oxo-1-p...)
Affinity DataEC50:  157nMAssay Description:Effect on [35S]GTP-gamma-S binding to human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKi:  5.37nMAssay Description:Displacement of [3H]SR-141716A from human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM21281(WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...)
Affinity DataKi:  9.10nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180026(N3-(2-adamantyl)-4-oxo-1-pentyl-1,4-dihydroquinoli...)
Affinity DataKi:  13.4nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKi:  15.4nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180020(4-oxo-1-pentyl-1,4-dihydro-quinoline-3-carboxylic ...)
Affinity DataKi:  15.8nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180040(N3-(1-adamantyl)-4-oxo-1-pentyl-1,4-dihydroquinoli...)
Affinity DataKi:  16.4nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180036(CHEMBL371214 | (6aR,10aR)-3-(1,1-dimethylbutyl)-6a...)
Affinity DataKi:  20.3nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180021((R)-N3-(1-phenylethyl)-4-oxo-1-pentyl-1,4-dihydroq...)
Affinity DataKi:  37.1nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  51.7nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180028((RS)-N3-(1-(1,2,3,4-tetrahydronaphthyl))-4-oxo-1-p...)
Affinity DataKi:  60.2nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180044((RS)-N3-(1-phenylethyl)-4-oxo-1-pentyl-1,4-dihydro...)
Affinity DataKi:  70.8nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180038((R)-N3-(1-(1-naphthyl)ethyl)-4-oxo-1-pentyl-1,4-di...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180030((RS)-N3-(1-(1-naphthyl)ethyl)-4-oxo-1-pentyl-1,4-d...)
Affinity DataKi:  174nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180041(N3-(phenethyl)-4-oxo-1-pentyl-1,4-dihydroquinoline...)
Affinity DataKi:  201nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180027(N3-(1-naphthyl)-4-oxo-1-pentyl-1,4-dihydroquinolin...)
Affinity DataKi:  371nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180039(N3-(2-(benzo[1,3]dioxol-5-yl)ethyl)-4-oxo-1-pentyl...)
Affinity DataKi:  426nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180042(N3-(1-naphthyl)-1-butyl-4-oxo-1,4-dihydroquinoline...)
Affinity DataKi:  455nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180032((R)-N3-(1-(2-naphthyl)ethyl)-4-oxo-1-pentyl-1,4-di...)
Affinity DataKi:  584nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180025(N3-(1-(3,5-dimethyl)adamantyl)-4-oxo-1-benzyl-1,4-...)
Affinity DataKi:  664nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180024(N3-(4-cyanophenyl)-4-oxo-1-pentyl-1,4-dihydroquino...)
Affinity DataKi:  772nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180037((S)-N3-(1-phenylethyl)-4-oxo-1-pentyl-1,4-dihydroq...)
Affinity DataKi:  784nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180031(N3-(1-naphthyl)-1-hexyl-4-oxo-1,4-dihydroquinoline...)
Affinity DataKi:  844nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180029((S)-N3-(1-(1-naphthyl)ethyl)-4-oxo-1-pentyl-1,4-di...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180033(N3-(3-phenylpropyl)-4-oxo-1-pentyl-1,4-dihydroquin...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180043((RS)-N3-(1-(2-naphthyl)ethyl)-4-oxo-1-pentyl-1,4-d...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180023(N3-(3,4-dichlorophenyl)-4-oxo-1-pentyl-1,4-dihydro...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180035(N3-(benzyl)-4-oxo-1-pentyl-1,4-dihydroquinoline-3-...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180028((RS)-N3-(1-(1,2,3,4-tetrahydronaphthyl))-4-oxo-1-p...)
Affinity DataKi:  1.05E+3nMAssay Description:Displacement of [3H]SR-141716A from human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180021((R)-N3-(1-phenylethyl)-4-oxo-1-pentyl-1,4-dihydroq...)
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [3H]SR-141716A from human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180026(N3-(2-adamantyl)-4-oxo-1-pentyl-1,4-dihydroquinoli...)
Affinity DataKi:  1.93E+3nMAssay Description:Displacement of [3H]SR-141716A from human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180027(N3-(1-naphthyl)-4-oxo-1-pentyl-1,4-dihydroquinolin...)
Affinity DataKi:  4.08E+3nMAssay Description:Displacement of [3H]SR-141716A from human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50180034((S)-N3-(1-(2-naphthyl)ethyl)-4-oxo-1-pentyl-1,4-di...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed