Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50000526
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50006906(CHEMBL23977 | 2-{4-[(2-Amino-4-oxo-3,4-dihydro-qui...)
Affinity DataKi:  67nMAssay Description:Binding affinity towards Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50006907(CHEMBL89641 | 2-{4-[(4-Oxo-3,4-dihydro-quinazolin-...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity towards Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50006905(CHEMBL316019 | 2-{4-[(4-Oxo-3,4-dihydro-benzo[d][1...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity towards Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50006905(CHEMBL316019 | 2-{4-[(4-Oxo-3,4-dihydro-benzo[d][1...)
Affinity DataKi:  2.80E+4nMAssay Description:Compound was tested for the inhibition of recombinant mouse thymidylate synthase, competitive with 5,10-methylenetetrahydrofolate as variable substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed