Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50017188
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178811(N-(3-aminopropyl)-4-tert-butyl-N,N-dimethylbenzena...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against trypanothione reductase from Trypanosoma cruzi using 0.12 mM TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178810(N-(5-chloro-2-(phenylthio)phenyl)butyramide | CHEM...)
Affinity DataIC50: 3.05E+4nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178808(N-(5-chloro-2-(phenylthio)phenyl)propionamide | CH...)
Affinity DataIC50: 3.16E+4nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178812(cid_2480386 | CHEMBL197131 | N-(5-chloro-2-(phenyl...)
Affinity DataIC50: 3.68E+4nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178806(N-(5-chloro-2-(phenylthio)phenyl)-4-nitrobenzamide...)
Affinity DataIC50: 4.45E+4nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178801(N-(5-chloro-2-(phenylthio)phenyl)benzamide | CHEMB...)
Affinity DataIC50: 4.96E+4nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178811(N-(3-aminopropyl)-4-tert-butyl-N,N-dimethylbenzena...)
Affinity DataKi:  150nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178803(3,4-dichloro-N-(3-(2-chloro-10H-phenothiazin-10-yl...)
Affinity DataKi:  180nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178803(3,4-dichloro-N-(3-(2-chloro-10H-phenothiazin-10-yl...)
Affinity DataKi:  440nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178809(4-tert-butyl-N-(3-(2-chloro-10H-phenothiazin-10-yl...)
Affinity DataKi:  570nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178807(3,4-dichloro-N-(3-(5-chloro-2-(phenylthio)phenylam...)
Affinity DataKi:  1.69E+3nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using (ZCG.dmapa)2 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178802(4-tert-butyl-N-(3-(5-chloro-2-(phenylthio)phenylam...)
Affinity DataKi:  2.67E+3nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178805(N-benzhydryl-3-(5-chloro-2-(phenylthio)phenylamino...)
Affinity DataKi:  5.30E+3nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using (ZCG.dmapa)2 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178802(4-tert-butyl-N-(3-(5-chloro-2-(phenylthio)phenylam...)
Affinity DataKi:  6.50E+3nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using (ZCG.dmapa)2 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178804(4-(benzyloxy)-N-(3-(5-chloro-2-(phenylthio)phenyla...)
Affinity DataKi:  6.60E+3nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using (ZCG.dmapa)2 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178810(N-(5-chloro-2-(phenylthio)phenyl)butyramide | CHEM...)
Affinity DataKi:  1.13E+4nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178814(N-(3-(5-chloro-2-(phenylthio)phenylamino)propyl)-N...)
Affinity DataKi:  1.42E+4nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using (ZCG.dmapa)2 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178808(N-(5-chloro-2-(phenylthio)phenyl)propionamide | CH...)
Affinity DataKi:  2.00E+4nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178801(N-(5-chloro-2-(phenylthio)phenyl)benzamide | CHEMB...)
Affinity DataKi:  2.45E+4nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178812(cid_2480386 | CHEMBL197131 | N-(5-chloro-2-(phenyl...)
Affinity DataKi:  2.46E+4nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178806(N-(5-chloro-2-(phenylthio)phenyl)-4-nitrobenzamide...)
Affinity DataKi:  4.28E+4nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178809(4-tert-butyl-N-(3-(2-chloro-10H-phenothiazin-10-yl...)
Affinity DataKi:  6.60E+4nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using (ZCG.dmapa)2 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50178813(2-amino-4-chloro-phenyl phenyl sulfide | CHEMBL197...)
Affinity DataKi:  1.50E+5nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed