Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50017114
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177643((R)-[8-chloro-6-(1-piperazinyl)-1H-benzo[5,6]]cycl...)
Affinity DataIC50: 7nMAssay Description:Inhibition of farnesyltransferase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177643((R)-[8-chloro-6-(1-piperazinyl)-1H-benzo[5,6]]cycl...)
Affinity DataIC50: 72nMAssay Description:Inhibition of farnesyltransferase activity in COS7 cells transfected with Ras gene in soft agar proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177642((R)-8-chloro-11-(1-methanesulfonyl-piperidin-4-yl)...)
Affinity DataIC50: 76nMAssay Description:Inhibition of farnesyltransferase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177641((S)-8-chloro-11-(1-methanesulfonyl-piperidin-4-yl)...)
Affinity DataIC50: 150nMAssay Description:Inhibition of farnesyltransferase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed