Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50037858
TargetPhenylethanolamine N-methyltransferase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM13014(7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...)
Affinity DataKi:  1.55nMAssay Description:Binding affinity to human wild type his-tagged PNMTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhenylethanolamine N-methyltransferase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM14060(CHEMBL26828 | 7-Iodo-1,2,3,4-tetrahydroisoquinolin...)
Affinity DataKi:  40nMAssay Description:Binding affinity to human wild type his-tagged PNMTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhenylethanolamine N-methyltransferase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM13017(1,2,3,4-tetrahydroisoquinoline-7-sulfonamide | CHE...)
Affinity DataKi:  120nMAssay Description:Binding affinity to human wild type his-tagged PNMTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhenylethanolamine N-methyltransferase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50100952(1-(2,3-Dichloro-phenyl)-ethylamine | 2,3-dichloro-...)
Affinity DataKi:  1.33E+3nMAssay Description:Binding affinity to human free PNMTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50072991(7-Nitro-1,2,3,4-tetrahydro-isoquinoline | 7-nitro-...)
Affinity DataKi:  2.36E+3nMAssay Description:Binding affinity to human free PNMTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50176888(3-trifluoromethylphenylethanolamine | CHEMBL224618)
Affinity DataKd:  2.40E+3nMAssay Description:Activity of human wild type PNMT assessed as phenylethanolamine methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhenylethanolamine N-methyltransferase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM13017(1,2,3,4-tetrahydroisoquinoline-7-sulfonamide | CHE...)
Affinity DataKi:  2.84E+3nMAssay Description:Binding affinity to human free PNMTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhenylethanolamine N-methyltransferase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50176889(anti-9-amino-6-(trifluoromethyl)benzonorbornene | ...)
Affinity DataKd:  4.40E+3nMAssay Description:Activity of human wild type PNMT assessed as phenylethanolamine methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM14061(8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine |...)
Affinity DataKi:  4.40E+3nMAssay Description:Binding affinity to human wild type his-tagged PNMTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhenylethanolamine N-methyltransferase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM28422((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...)
Affinity DataKd:  4.80E+3nMAssay Description:Activity of human wild type PNMT assessed as phenylethanolamine methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50176890(2-(3,4-Dichloro-phenyl)-1-methyl-ethylamine | 3,4-...)
Affinity DataKi:  1.48E+4nMAssay Description:Binding affinity to human free PNMTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50176887(phenylethanolamine | CHEMBL224526)
Affinity DataKd:  1.80E+5nMAssay Description:Activity of human wild type PNMT assessed as phenylethanolamine methylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed