Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50017010
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataEC50:  1.10E+3nMAssay Description:cAMP elevation in U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataEC50:  22nMAssay Description:cAMP elevation in U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PAF mediated human eosinophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of C5a mediated human eosinophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 2nMAssay Description:Inhibition of release of LTE4 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Eotaxin mediated by human eosinophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 4nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 11nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 33nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 34nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 41nMAssay Description:Inhibition of release of LTE4 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 41nMAssay Description:Inhibition of release of LTE4 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 107nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 185nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 625nMAssay Description:Inhibition of release of TNF alpha in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 925nMAssay Description:Inhibition of release of TNF alpha in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of PDE4CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PAF mediated human eosinophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of PDE4CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of LTB4 mediated human eosinophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PDE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PDE9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PDE3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PDE9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PDE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PDE10More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PDE10More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PDE11More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PDE3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of C5a mediated human eosinophil chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)