Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50016976
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175995(N-(2,4-difluorophenyl)-3-(5-(3-(dimethylamino)prop...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176013(3-(6-(2,4-difluorophenylamino)-1H-pyrazolo[3,4-b]p...)
Affinity DataIC50: 0.700nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176003(N-(2,4-difluorophenyl)-3-(2-methoxy-5-(3-(4-methyl...)
Affinity DataIC50: 0.900nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175994(N-cyclopentyl-3-(6-(2,4-difluorophenylamino)-1H-py...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175998(4-(3-(6-(2,4-difluorophenylamino)-1H-pyrazolo[3,4-...)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176006(3-(5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176010(N-(2,4-difluorophenyl)-3-(5-(3-(dimethylamino)prop...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176000(3-(5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176005(N-(2,4-difluorophenyl)-3-(2-methoxy-5-(3-(4-methyl...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175999(4-(3-(6-(2,4-difluorophenylamino)-1H-pyrazolo[3,4-...)
Affinity DataIC50: 19nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176007(3-(5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176001(4-(3-(6-(2,4-difluorophenylamino)-1H-pyrazolo[3,4-...)
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176004(3-(5-(3-amino-3-methylbutyl)-2-methoxyphenyl)-N-(2...)
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176002(3-(5-(3-amino-3-methylbutyl)-2-methoxyphenyl)-N-(2...)
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176008(3-(5-(3-amino-3-methylbutyl)-2-methoxyphenyl)-N-(2...)
Affinity DataIC50: 43nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176009(4-(3-(6-(2,4-difluorophenylamino)-1H-pyrazolo[3,4-...)
Affinity DataIC50: 47nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176011(3-(5-((cyclopentylamino)methyl)-2-methoxyphenyl)-N...)
Affinity DataIC50: 58nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175996(N-(2,4-difluorophenyl)-3-(2-methoxy-5-((tetrahydro...)
Affinity DataIC50: 94nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175997(3-(6-(2,4-difluorophenylamino)-1H-pyrazolo[3,4-b]p...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176012((3-(6-(2,4-difluorophenylamino)-1H-pyrazolo[3,4-b]...)
Affinity DataIC50: 280nMAssay Description:Inhibitory activity against murine p38-alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176000(3-(5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity against c-MetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176000(3-(5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176000(3-(5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibitory activity against HER1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176000(3-(5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibitory activity against JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50176007(3-(5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175998(4-(3-(6-(2,4-difluorophenylamino)-1H-pyrazolo[3,4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed