Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50016947
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175665((R)-(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)...)
Affinity DataIC50: 10nMAssay Description:Calcium mobilization mediated by CCR4 receptor in CEMS529 cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175665((R)-(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)...)
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175661((R)-(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)...)
Affinity DataIC50: 60nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175671((4-(2-(2,4-dichlorobenzylamino)pyrimidin-4-yl)pipe...)
Affinity DataIC50: 300nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175665((R)-(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)...)
Affinity DataIC50: 380nMAssay Description:Inhibition of chemotaxis of murine CCR4 transfected L1.2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175664((4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)pipe...)
Affinity DataIC50: 700nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175667((4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)pipe...)
Affinity DataIC50: 800nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175659((S)-(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175673((4-(4-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)pipera...)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175670(N-((S)-1-(4-(2,4-dichlorobenzyloxy)pyrimidin-2-yla...)
Affinity DataIC50: 5.60E+3nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175672((4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)pipe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175669((4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)pipe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175668(1-(4-(4-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)pipe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175666(N-(2-(4-(2,4-dichlorobenzyloxy)pyrimidin-2-ylamino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175663((4-(4-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)pipera...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175662(N-(3-(4-(2,4-dichlorobenzyloxy)pyrimidin-2-ylamino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175660(1-(4-(4-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)pipe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed