Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 1124
TargetCholinesterase(Human)
Neuropharma

LigandPNGBDBM9063(5,6-dimethoxy-2-({[7-(1,2,3,4-tetrahydroacridin-9-...)
Affinity DataIC50: 0.600nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM9073(2-[9-(Acridin-9-ylamino)-nonyl]-isoindole-1,3-dion...)
Affinity DataIC50: 2.40nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM9067(N-{4-[{2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl...)
Affinity DataIC50: 2.80nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
Neuropharma

LigandPNGBDBM9070(2-[6-(acridin-9-ylamino)hexyl]-2,3-dihydro-1H-isoi...)
Affinity DataIC50: 7.80nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM9065(N-[6-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamin...)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
Neuropharma

LigandPNGBDBM9068(2-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-...)
Affinity DataIC50: 10nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 19nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM9066(N-[7-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamin...)
Affinity DataIC50: 20nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
Neuropharma

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 24nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM9063(5,6-dimethoxy-2-({[7-(1,2,3,4-tetrahydroacridin-9-...)
Affinity DataIC50: 25nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
Neuropharma

LigandPNGBDBM9069(2-[8-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-octyl]...)
Affinity DataIC50: 29nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
Neuropharma

LigandPNGBDBM9062(5,6-dimethoxy-2-({[6-(1,2,3,4-tetrahydroacridin-9-...)
Affinity DataIC50: 50nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
Neuropharma

LigandPNGBDBM9067(N-{4-[{2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl...)
Affinity DataIC50: 75nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
Neuropharma

LigandPNGBDBM9073(2-[9-(Acridin-9-ylamino)-nonyl]-isoindole-1,3-dion...)
Affinity DataIC50: 90nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM9069(2-[8-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-octyl]...)
Affinity DataIC50: 93nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
Neuropharma

LigandPNGBDBM9064(2-({[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]...)
Affinity DataIC50: 98nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM9062(5,6-dimethoxy-2-({[6-(1,2,3,4-tetrahydroacridin-9-...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 167nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Human)
Neuropharma

LigandPNGBDBM9065(N-[6-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamin...)
Affinity DataIC50: 220nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM9064(2-({[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]...)
Affinity DataIC50: 504nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
Neuropharma

LigandPNGBDBM9066(N-[7-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamin...)
Affinity DataIC50: 660nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
Neuropharma

LigandPNGBDBM9071(2-[7-(acridin-9-ylamino)heptyl]-2,3-dihydro-1H-iso...)
Affinity DataIC50: 711nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM9070(2-[6-(acridin-9-ylamino)hexyl]-2,3-dihydro-1H-isoi...)
Affinity DataIC50: 870nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
Neuropharma

LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 930nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
Neuropharma

LigandPNGBDBM9072(2-[8-(acridin-9-ylamino)octyl]-2,3-dihydro-1H-isoi...)
Affinity DataIC50: 1.01E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM9072(2-[8-(acridin-9-ylamino)octyl]-2,3-dihydro-1H-isoi...)
Affinity DataIC50: 1.14E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM9071(2-[7-(acridin-9-ylamino)heptyl]-2,3-dihydro-1H-iso...)
Affinity DataIC50: 1.55E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM9068(2-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-...)
Affinity DataIC50: 3.01E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed