Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 998
LigandPNGBDBM7887(1-benzylimidazole | 1-Benzylimidazole (BI) | CHEMB...)
Affinity DataKi:  6.40E+3nM ΔG°:  -30.1kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM7970(diethyl(2-sulfanylethyl)amine | N-diethylcysteamin...)
Affinity DataKi:  1.09E+4nM ΔG°:  -28.8kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7884(1-methyl-1H-imidazole | US9138393, 1-Methylimidazo...)
Affinity DataKi:  2.30E+4nM ΔG°:  -26.9kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7969(dimethyl(2-sulfanylethyl)amine | N-dimethylcysteam...)
Affinity DataKi:  2.90E+4nM ΔG°:  -26.3kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7968(2-aminoethane-1-thiol | Cysteamine)
Affinity DataKi:  4.20E+4nM ΔG°:  -25.4kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7882(CHEMBL540 | 1H-imidazole | imidazole | Imidazole (...)
Affinity DataKi:  1.60E+5nM ΔG°:  -22.0kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7939(1H-1,3-benzodiazole | Benzimidazole | Benzimidazol...)
Affinity DataKi:  1.92E+5nM ΔG°:  -21.6kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7971(2-sulfanylethan-1-ol | Mercaptoethanol)
Affinity DataKi:  2.58E+6nM ΔG°:  -15.0kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7972(ethane-1,2-diamine | CHEMBL816 | ethylenediamine)
Affinity DataKi:  2.20E+7nM ΔG°:  -9.62kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7973(CHEMBL104943 | 2-aminoethan-1-ol | ethanolamine)
Affinity DataKi:  1.93E+7nM ΔG°:  -9.95kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed