Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50016774
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173468(4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin...)
Affinity DataIC50: 0.0300nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173482(4-(2-Oxo-4-phenyl-2,3-dihydro-imidazol-1-yl)-piper...)
Affinity DataIC50: 0.0500nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173468(4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin...)
Affinity DataIC50: 0.0600nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in marmoset tissue homogenates using [125I]CGRP as radioligand after 180 minutes of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173475(4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin...)
Affinity DataIC50: 0.200nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173475(4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin...)
Affinity DataIC50: 2.70nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in marmoset tissue homogenates using [125I]CGRP as radioligand after 180 minutes of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173472(4-(1-Phenyl-ureido)-piperidine-1-carboxylic acid [...)
Affinity DataIC50: 4.70nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rat)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173468(4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin...)
Affinity DataIC50: 6.40nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in rat spleen using [125I]CGRP as radioligand after 180 minutes of incubation at pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173486(4-(2-Oxo-benzooxazol-3-yl)-piperidine-1-carboxylic...)
Affinity DataIC50: 44nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rat)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173475(4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin...)
Affinity DataIC50: 56.7nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in rat spleen using [125I]CGRP as radioligand after 180 minutes of incubation at pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173477((S)-N-[(R)-5-Amino-1-(4-pyridin-4-yl-piperazine-1-...)
Affinity DataIC50: 200nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173473(4-(2-Methoxy-phenyl)-piperazine-1-carboxylic acid ...)
Affinity DataIC50: 226nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173478(4-(2-Methoxy-phenyl)-piperidine-1-carboxylic acid ...)
Affinity DataIC50: 250nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173476((S)-N-[(R)-5-Amino-1-(4-pyridin-4-yl-piperazine-1-...)
Affinity DataIC50: 1.00E+3nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173471(N-{(S)-2-(4-Amino-3,5-dibromo-phenyl)-1-[(R)-5-ami...)
Affinity DataIC50: 1.03E+4nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173467((R)-6-Amino-2-((S)-3-(3,5-dibromo-4-hydroxy-phenyl...)
Affinity DataIC50: 1.30E+4nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173479((R)-6-Amino-2-[(S)-3-(3,5-dibromo-4-hydroxy-phenyl...)
Affinity DataIC50: 1.70E+4nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173485((R)-6-Amino-2-[(S)-3-(4-amino-3,5-dibromo-phenyl)-...)
Affinity DataIC50: 4.00E+4nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173484((R)-6-Amino-2-[(S)-3-(4-amino-3,5-dibromo-phenyl)-...)
Affinity DataIC50: 5.00E+4nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rat)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173477((S)-N-[(R)-5-Amino-1-(4-pyridin-4-yl-piperazine-1-...)
Affinity DataIC50: 7.05E+4nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in rat spleen using [125I]CGRP as radioligand after 180 minutes of incubation at pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173481((R)-6-Amino-2-[(S)-3-(4-amino-3,5-dibromo-phenyl)-...)
Affinity DataIC50: 1.96E+5nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173474(N-{(S)-2-(4-Amino-3,5-dibromo-phenyl)-1-[(R)-5-ami...)
Affinity DataIC50: 3.00E+5nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173480(N-{(S)-2-(4-Amino-3,5-dibromo-phenyl)-1-[(R)-5-ami...)
Affinity DataIC50: 3.00E+5nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173470((R)-6-Amino-2-[(R)-3-(3,5-dibromo-4-hydroxy-phenyl...)
Affinity DataIC50: 3.00E+5nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173469((S)-6-Amino-2-[(S)-3-(3,5-dibromo-4-hydroxy-phenyl...)
Affinity DataIC50: 3.00E+5nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173483((S)-6-Amino-2-[(R)-3-(3,5-dibromo-4-hydroxy-phenyl...)
Affinity DataIC50: 3.00E+5nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed