Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 1652
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM7842(BAY 59-7939 Analog 17 | US8822458, 46)
Affinity DataIC50: 0.400nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM7840(RIVAROXABAN | US8822458, 97 | US8822458, 44)
Affinity DataIC50: 0.700nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM12998(5-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)
Affinity DataIC50: 1nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM12997(5-Chloro-N-({(5S)-3-[3-fluoro-4-(3-oxomorpholin-4-...)
Affinity DataIC50: 1.40nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM12999(N-({(5S)-3-[3-Amino-4-(3-oxomorpholin-4-yl)phenyl]...)
Affinity DataIC50: 2.5nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM7552(BAY 59-7939 Analog 11 | US8822458, 17)
Affinity DataIC50: 4nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM7841(BAY 59-7939 Analog 18 | US8822458, 45 | US9359341,...)
Affinity DataIC50: 4.20nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM13008(4-Amino-5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorphol...)
Affinity DataIC50: 8.5nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM13005(4-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)
Affinity DataIC50: 20nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM13004(5-Bromo-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)p...)
Affinity DataIC50: 26nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM13010(5-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)
Affinity DataIC50: 29nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM12990(5-chloro-N-{[(5S)-3-[3-fluoro-4-(morpholin-4-yl)ph...)
Affinity DataIC50: 32nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM12992(5-chloro-N-{[(5S)-3-[3-fluoro-4-(pyrrolidin-1-yl)p...)
Affinity DataIC50: 40nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM7495(BAY 59-7939 Analog 7 | US8822458, 2)
Affinity DataIC50: 43nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM12993(5-Chloro-N-({(5S)-3-[4-(dimethylamino)phenyl]-2-ox...)
Affinity DataIC50: 74nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM12988(5-chloro-N-{[(5S)-3-[3-fluoro-4-(thiomorpholin-4-y...)
Affinity DataIC50: 90nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM13011(6-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)
Affinity DataIC50: 94nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM7532(BAY 59-7939 Analog 10 | US8822458, 11)
Affinity DataIC50: 140nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM13012(5-chloro-N-methyl-N-{[(5S)-2-oxo-3-[4-(3-oxomorpho...)
Affinity DataIC50: 197nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM13009(2-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)
Affinity DataIC50: 290nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM13006(3-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)
Affinity DataIC50: 1.17E+3nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM13013(5-chloro-N-{[(5R)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)
Affinity DataIC50: 1.20E+3nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM7632(BAY 59-7939 Analog 15 | US8822458, 36)
Affinity DataIC50: 1.26E+3nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM13007(2-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)
Affinity DataIC50: 2.00E+3nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Healthcare

LigandPNGBDBM13001(5-chloro-N-{[(5R)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)
Affinity DataIC50: 2.30E+3nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed