Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50037531
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21724(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...)
Affinity DataEC50:  70nMAssay Description:Activation of human farnesoid X receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21675(6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...)
Affinity DataEC50:  99nMAssay Description:Activation of human farnesoid X receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21674(Chenodeoxycholic Acid | CDCA | (4R)-4-[(1S,2S,5R,7...)
Affinity DataEC50:  3.50E+3nMAssay Description:Effective concentration for recruitment of SRC-1 LxxLL-containing peptide to human Farnesoid X receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21674(Chenodeoxycholic Acid | CDCA | (4R)-4-[(1S,2S,5R,7...)
Affinity DataEC50:  3.00E+4nMAssay Description:Activation of human farnesoid X receptor; range is 10-30More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50171846((E)-3-{3-[(4-Benzo[1,3]dioxol-5-yl-benzyl)-cyclohe...)
Affinity DataEC50:  2.22E+5nMAssay Description:Activation of human farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50171848((E)-3-{3-[Cyclohexanecarbonyl-(4-styryl-benzyl)-am...)
Affinity DataEC50:  2.55E+5nMAssay Description:Activation of human farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50171847((E)-3-{3-[Cyclohexanecarbonyl-(4'-dimethylamino-bi...)
Affinity DataEC50:  2.55E+5nMAssay Description:Activation of human farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed