Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50016643
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171516(N-[4-(4,5-Dichloro-2-fluoro-phenylamino)-quinazoli...)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171514(2-Chloro-N-[4-(4,5-dichloro-2-fluoro-phenylamino)-...)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171520((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171525(2-Chloro-N-[4-(3-iodo-phenylamino)-quinazolin-6-yl...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171523((4,5-Dichloro-2-fluoro-phenyl)-(6,7-dimethoxy-quin...)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM4583((2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4...)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171524((E)-4-Dimethylamino-but-2-enoic acid [4-(3-iodo-ph...)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171520((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HER1 kinase in intact DHER14 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171524((E)-4-Dimethylamino-but-2-enoic acid [4-(3-iodo-ph...)
Affinity DataIC50: 5nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171518(N-[4-(3-Bromo-phenylamino)-quinazolin-6-yl]-2-chlo...)
Affinity DataIC50: 5nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171524((E)-4-Dimethylamino-but-2-enoic acid [4-(3-iodo-ph...)
Affinity DataIC50: 5nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171523((4,5-Dichloro-2-fluoro-phenyl)-(6,7-dimethoxy-quin...)
Affinity DataIC50: 5nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 3-5 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM4583((2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4...)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 1-10 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171520((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 4-10 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM4583((2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4...)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 1-10 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171518(N-[4-(3-Bromo-phenylamino)-quinazolin-6-yl]-2-chlo...)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171525(2-Chloro-N-[4-(3-iodo-phenylamino)-quinazolin-6-yl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 4-10 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171514(2-Chloro-N-[4-(4,5-dichloro-2-fluoro-phenylamino)-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of HER1 kinase in intact DHER14 cells; Range = 5-15 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171516(N-[4-(4,5-Dichloro-2-fluoro-phenylamino)-quinazoli...)
Affinity DataIC50: 20nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 6.7-20 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171516(N-[4-(4,5-Dichloro-2-fluoro-phenylamino)-quinazoli...)
Affinity DataIC50: 20nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 6.7-20 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171514(2-Chloro-N-[4-(4,5-dichloro-2-fluoro-phenylamino)-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 5-25 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171514(2-Chloro-N-[4-(4,5-dichloro-2-fluoro-phenylamino)-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 25-50 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171525(2-Chloro-N-[4-(3-iodo-phenylamino)-quinazolin-6-yl...)
Affinity DataIC50: 30nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171518(N-[4-(3-Bromo-phenylamino)-quinazolin-6-yl]-2-chlo...)
Affinity DataIC50: 32nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171520((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...)
Affinity DataIC50: 50nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 10-50 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171514(2-Chloro-N-[4-(4,5-dichloro-2-fluoro-phenylamino)-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of HER2 kinase in intact CSH12 cells; Range = 25-50 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171520((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...)
Affinity DataIC50: 50nMAssay Description:Inhibition of HER2 kinase in intact CSH12 cells; Range = 25-50 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171522(N-[4-(3-Iodo-phenylamino)-quinazolin-6-yl]-2-metho...)
Affinity DataIC50: 150nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171521(N-[4-(3-Bromo-phenylamino)-quinazolin-6-yl]-2-meth...)
Affinity DataIC50: 174nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171517(N-[4-(4,5-Dichloro-2-fluoro-phenylamino)-7-(4-meth...)
Affinity DataIC50: 250nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171519(N-[4-(3-Bromo-phenylamino)-7-(4-methyl-piperazin-1...)
Affinity DataIC50: 250nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 50-250 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171515(N-[4-(4,5-Dichloro-2-fluoro-phenylamino)-quinazoli...)
Affinity DataIC50: 250nMAssay Description:Inhibition of HER1 kinase in intact DHER14 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171515(N-[4-(4,5-Dichloro-2-fluoro-phenylamino)-quinazoli...)
Affinity DataIC50: 252nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171515(N-[4-(4,5-Dichloro-2-fluoro-phenylamino)-quinazoli...)
Affinity DataIC50: 500nMAssay Description:Inhibition of HER2 kinase in intact CSH12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171519(N-[4-(3-Bromo-phenylamino)-7-(4-methyl-piperazin-1...)
Affinity DataIC50: 500nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171517(N-[4-(4,5-Dichloro-2-fluoro-phenylamino)-7-(4-meth...)
Affinity DataIC50: 500nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171515(N-[4-(4,5-Dichloro-2-fluoro-phenylamino)-quinazoli...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human PDGFR kinase in intact NIHPDGFR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171520((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human PDGFR kinase in intact NIHPDGFR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171514(2-Chloro-N-[4-(4,5-dichloro-2-fluoro-phenylamino)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human PDGFR kinase in intact NIHPDGFR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171522(N-[4-(3-Iodo-phenylamino)-quinazolin-6-yl]-2-metho...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 1000-5000 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171517(N-[4-(4,5-Dichloro-2-fluoro-phenylamino)-7-(4-meth...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171515(N-[4-(4,5-Dichloro-2-fluoro-phenylamino)-quinazoli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 1000-10000 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171519(N-[4-(3-Bromo-phenylamino)-7-(4-methyl-piperazin-1...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171521(N-[4-(3-Bromo-phenylamino)-quinazolin-6-yl]-2-meth...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171515(N-[4-(4,5-Dichloro-2-fluoro-phenylamino)-quinazoli...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 10000-50000 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171522(N-[4-(3-Iodo-phenylamino)-quinazolin-6-yl]-2-metho...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171521(N-[4-(3-Bromo-phenylamino)-quinazolin-6-yl]-2-meth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed