Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50037525
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50171301((S)-(2-{3-[((9S,12S)-12-Cyclohexyl-11,14-dioxo-2-o...)
Affinity DataKi:  110nMAssay Description:Ability to inhibit the hydrolysis of chromogenic 4-phenylazophenyl ester from the peptide fragment Ac- DTEDVVP(Nva)-O-4-PAP in a HCV protease continu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50171302((S)-(2-{3-[((9S,12S)-12-Cyclohexyl-11,14-dioxo-2-o...)
Affinity DataKi:  160nMAssay Description:Ability to inhibit the hydrolysis of chromogenic 4-phenylazophenyl ester from the peptide fragment Ac- DTEDVVP(Nva)-O-4-PAP in a HCV protease continu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50171302((S)-(2-{3-[((9S,12S)-12-Cyclohexyl-11,14-dioxo-2-o...)
Affinity DataKi:  300nMAssay Description:Ability to inhibit the hydrolysis of chromogenic 4-chlorophenylbutyric acid ester from the peptide fragment Ac- DTEDVVP(Nva)-O-4-PAP in a HCV proteas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50171305((S)-(2-{3-[((9S,12S)-12-Cyclohexyl-11,14-dioxo-2-o...)
Affinity DataKi:  300nMAssay Description:Ability to inhibit the hydrolysis of chromogenic 4-phenylazophenyl ester from the peptide fragment Ac- DTEDVVP(Nva)-O-4-PAP in a HCV protease continu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50370596(CHEMBL1169404)
Affinity DataKi:  800nMAssay Description:Ability to inhibit the hydrolysis of chromogenic 4-phenylazophenyl ester from the peptide fragment Ac- DTEDVVP(Nva)-O-4-PAP in a HCV protease continu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50171301((S)-(2-{3-[((9S,12S)-12-Cyclohexyl-11,14-dioxo-2-o...)
Affinity DataKi:  2.90E+3nMAssay Description:Binding constant towards Human neutrophil elastase HNE proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50171304((S)-(2-{(S)-3-[((9S,12S,15S)-15-tert-Butoxycarbony...)
Affinity DataKi:  7.80E+3nMAssay Description:Ability to inhibit the hydrolysis of chromogenic 4-phenylazophenyl ester from the peptide fragment Ac- DTEDVVP(Nva)-O-4-PAP in a HCV protease continu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50171303({3-[((9S,12S,15S)-15-tert-Butoxycarbonylamino-12-c...)
Affinity DataKi:  1.20E+4nMAssay Description:Ability to inhibit the hydrolysis of chromogenic 4-phenylazophenyl ester from the peptide fragment Ac- DTEDVVP(Nva)-O-4-PAP in a HCV protease continu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed