Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50016615
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171241(2-Phenyl-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-in...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171235(5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataIC50: 7.40nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171235(5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataIC50: 7.40nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 6 receptor in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171237(5-Chloro-2-methyl-3-(1-methyl-1,2,3,6-tetrahydro-p...)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171242(5-Chloro-3-(1-ethyl-1,2,3,6-tetrahydro-pyridin-4-y...)
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171239(5-Chloro-2-ethyl-3-(1,2,3,6-tetrahydro-pyridin-4-y...)
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171235(5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataIC50: 34nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor expressed in NG 108 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171243(5-Chloro-2-methyl-3-(8-methyl-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171234([2-(5-Chloro-2-methyl-1H-indol-3-yl)-ethyl]-dimeth...)
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171245(5-Chloro-2-propyl-3-(1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | EMDT | ...)
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 4 receptor in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171240(3-(1-Butyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-chlo...)
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171246(5-Chloro-2-methyl-3-(1-propyl-1,2,3,6-tetrahydro-p...)
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171244(5-Chloro-2-ethyl-3-(1-ethyl-1,2,3,6-tetrahydro-pyr...)
Affinity DataIC50: 70nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM81498(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)
Affinity DataIC50: 79nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171236(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 6 receptor in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171236(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | EMDT | ...)
Affinity DataIC50: 85nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor stably expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | EMDT | ...)
Affinity DataIC50: 85nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 6 receptor in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171233(2-Ethyl-5-methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataIC50: 90nMAssay Description:Displacement of [3H]LSD binding to cloned h5-HT6 receptors stably expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171238(5-Chloro-2-isopropyl-3-(1,2,3,6-tetrahydro-pyridin...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171235(5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor in calfMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171235(5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171235(5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataIC50: 240nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 2A receptor in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171247(2-Ethyl-5-methoxy-3-piperidin-4-yl-1H-indole | CHE...)
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]LSD binding to cloned h5-HT6 receptors stably expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171236(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171236(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Affinity DataIC50: 430nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171235(5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataIC50: 450nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 2C receptor in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171248(3-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-chl...)
Affinity DataIC50: 600nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171235(5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataIC50: 620nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 4 receptor in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | EMDT | ...)
Affinity DataIC50: 620nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 2A receptor in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171235(5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataIC50: 660nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171236(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 2A receptor in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171236(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor expressed in NG 108 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | EMDT | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | EMDT | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor expressed in NG 108 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171236(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor in calfMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | EMDT | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171236(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 2C receptor in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | EMDT | ...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor in calfMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | EMDT | ...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 7 receptor in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171235(5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 7 receptor in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | EMDT | ...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 2C receptor in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171236(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 4 receptor in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171236(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 7 receptor in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed