Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50016570
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170833(5-[8-(Isopropyl-methyl-amino)-9-methyl-9H-purin-6-...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity for human adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170830(N*6*-Cycloheptyl-N*2*-phenyl-9H-purine-2,6-diamine...)
Affinity DataKi:  42nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170816(Cyclohexyl-(2-phenoxy-9H-purin-6-yl)-amine | CHEMB...)
Affinity DataKi:  47nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170822(N*6*-Cyclohexyl-N*2*-phenyl-9H-purine-2,6-diamine ...)
Affinity DataKi:  51nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170823(N*6*-Cyclohexyl-N*2*-(4-dimethylamino-phenyl)-9H-p...)
Affinity DataKi:  70nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170817(N*6*-Cyclohexyl-9-methyl-N*2*-phenyl-9H-purine-2,6...)
Affinity DataKi:  70nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170827(N*6*-Bicyclo[2.2.1]hept-2-yl-N*2*-(4-morpholin-4-y...)
Affinity DataKi:  122nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170818(Cyclohexyl-(2-phenylsulfanyl-9H-purin-6-yl)-amine ...)
Affinity DataKi:  134nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170821(N*6*-Cyclooctyl-N*2*-phenyl-9H-purine-2,6-diamine ...)
Affinity DataKi:  340nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170838(N*6*-Cycloheptyl-N*2*-(4-morpholin-4-yl-phenyl)-9H...)
Affinity DataKi:  420nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170831(N*6*-Cyclohexyl-N*2*-(4-morpholin-4-yl-phenyl)-9H-...)
Affinity DataKi:  660nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170836(N*2*-Benzyl-N*6*-cyclohexyl-9H-purine-2,6-diamine ...)
Affinity DataKi:  920nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170826(N*6*-Cycloheptyl-9-methyl-N*2*-phenyl-9H-purine-2,...)
Affinity DataKi:  960nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170815(N*6*-Cyclohexyl-N*2*-ethyl-9H-purine-2,6-diamine |...)
Affinity DataKi:  1.12E+3nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170817(N*6*-Cyclohexyl-9-methyl-N*2*-phenyl-9H-purine-2,6...)
Affinity DataKi:  1.20E+3nMAssay Description:Percent inhibition of [3H]ZM241,385 binding to human adenosine A2a receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170828(N*6*-Cyclopentyl-N*2*-(4-morpholin-4-yl-phenyl)-9H...)
Affinity DataKi:  1.39E+3nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170820(N*6*-Cyclohexyl-N*2*-(2-ethyl-phenyl)-9H-purine-2,...)
Affinity DataKi:  1.46E+3nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170829(N*6*-Ethyl-N*2*-(4-morpholin-4-yl-phenyl)-9H-purin...)
Affinity DataKi:  1.53E+3nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170832(N*6*-Cyclohexyl-N*2*-(4-phenyl-piperidin-1-yl)-9H-...)
Affinity DataKi:  1.57E+3nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170822(N*6*-Cyclohexyl-N*2*-phenyl-9H-purine-2,6-diamine ...)
Affinity DataKi:  1.70E+3nMAssay Description:Percent inhibition of [3H]ZM241,385 binding to human adenosine A2a receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170830(N*6*-Cycloheptyl-N*2*-phenyl-9H-purine-2,6-diamine...)
Affinity DataKi:  1.72E+3nMAssay Description:Percent inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170825(N*6*-Cyclobutyl-N*2*-(4-morpholin-4-yl-phenyl)-9H-...)
Affinity DataKi:  1.81E+3nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170834(N*6*-Cyclopropyl-N*2*-(4-morpholin-4-yl-phenyl)-9H...)
Affinity DataKi:  1.87E+3nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170817(N*6*-Cyclohexyl-9-methyl-N*2*-phenyl-9H-purine-2,6...)
Affinity DataKi:  1.88E+3nMAssay Description:Percent inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170826(N*6*-Cycloheptyl-9-methyl-N*2*-phenyl-9H-purine-2,...)
Affinity DataKi:  1.94E+3nMAssay Description:Percent inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170824(6-N-cyclohexyl-2-N-(naphthalen-2-yl)-1H-purine-2,6...)
Affinity DataKi:  2.42E+3nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170822(N*6*-Cyclohexyl-N*2*-phenyl-9H-purine-2,6-diamine ...)
Affinity DataKi:  2.73E+3nMAssay Description:Percent inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170837(N*6*-Cyclooctyl-N*2*-(4-morpholin-4-yl-phenyl)-9H-...)
Affinity DataKi:  2.77E+3nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170826(N*6*-Cycloheptyl-9-methyl-N*2*-phenyl-9H-purine-2,...)
Affinity DataKi:  2.95E+3nMAssay Description:Percent inhibition of [3H]ZM241,385 binding to human adenosine A2a receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170818(Cyclohexyl-(2-phenylsulfanyl-9H-purin-6-yl)-amine ...)
Affinity DataKi:  3.00E+3nMAssay Description:Percent inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170820(N*6*-Cyclohexyl-N*2*-(2-ethyl-phenyl)-9H-purine-2,...)
Affinity DataKi:  3.17E+3nMAssay Description:Percent inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170823(N*6*-Cyclohexyl-N*2*-(4-dimethylamino-phenyl)-9H-p...)
Affinity DataKi:  3.90E+3nMAssay Description:Percent inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170830(N*6*-Cycloheptyl-N*2*-phenyl-9H-purine-2,6-diamine...)
Affinity DataKi:  4.12E+3nMAssay Description:Percent inhibition of [3H]ZM241,385 binding to human adenosine A2a receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170821(N*6*-Cyclooctyl-N*2*-phenyl-9H-purine-2,6-diamine ...)
Affinity DataKi:  4.47E+3nMAssay Description:Percent inhibition of [3H]-DPCPX binding to human adenosine A1 receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170839(N*2*-Biphenyl-4-yl-N*6*-cyclohexyl-9H-purine-2,6-d...)
Affinity DataKi:  5.40E+3nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170823(N*6*-Cyclohexyl-N*2*-(4-dimethylamino-phenyl)-9H-p...)
Affinity DataKi:  6.10E+3nMAssay Description:Percent inhibition of [3H]ZM241,385 binding to human adenosine A2a receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170831(N*6*-Cyclohexyl-N*2*-(4-morpholin-4-yl-phenyl)-9H-...)
Affinity DataKi: >1.00E+4nMAssay Description:Percent inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170831(N*6*-Cyclohexyl-N*2*-(4-morpholin-4-yl-phenyl)-9H-...)
Affinity DataKi: >1.00E+4nMAssay Description:Percent inhibition of [3H]ZM241,385 binding to human adenosine A2a receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170818(Cyclohexyl-(2-phenylsulfanyl-9H-purin-6-yl)-amine ...)
Affinity DataKi:  1.40E+4nMAssay Description:Percent inhibition of [3H]ZM241,385 binding to human adenosine A2a receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170816(Cyclohexyl-(2-phenoxy-9H-purin-6-yl)-amine | CHEMB...)
Affinity DataKi:  1.60E+4nMAssay Description:Percent inhibition of [3H]ZM241,385 binding to human adenosine A2a receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170816(Cyclohexyl-(2-phenoxy-9H-purin-6-yl)-amine | CHEMB...)
Affinity DataKi:  2.60E+4nMAssay Description:Percent inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170827(N*6*-Bicyclo[2.2.1]hept-2-yl-N*2*-(4-morpholin-4-y...)
Affinity DataKi:  3.40E+4nMAssay Description:Percent inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170827(N*6*-Bicyclo[2.2.1]hept-2-yl-N*2*-(4-morpholin-4-y...)
Affinity DataKi:  3.90E+4nMAssay Description:Percent inhibition of [3H]ZM241,385 binding to human adenosine A2a receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170821(N*6*-Cyclooctyl-N*2*-phenyl-9H-purine-2,6-diamine ...)
Affinity DataKi:  4.60E+4nMAssay Description:Percent inhibition of [3H]ZM241,385 binding to human adenosine A2a receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed