Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50016546
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170318(1-(2,2-Dimethyl-propyl)-2-methyl-4-propyl-5-{4-[4-...)
Affinity DataEC50:  559nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170327(1-(2,2-Dimethyl-propyl)-4-propyl-5-{5-[4-(1H-tetra...)
Affinity DataEC50:  1.01E+3nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170326(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  559nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170329(1-Isobutyl-4-propyl-5-{4-[4-(1H-tetrazol-5-yl)-phe...)
Affinity DataEC50:  765nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170328(1-(2,2-Dimethyl-propyl)-4-propyl-5-{3-[4-(1H-tetra...)
Affinity DataEC50:  3.54E+3nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170324(1-Cyclohexylmethyl-4-propyl-5-{4-[4-(1H-tetrazol-5...)
Affinity DataEC50:  228nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170325(1-Cyclopropylmethyl-4-propyl-5-{4-[4-(1H-tetrazol-...)
Affinity DataEC50:  755nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170312(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  188nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170323(1-(2,2-Dimethyl-propyl)-4-propyl-5-{2-[4-(1H-tetra...)
Affinity DataEC50:  1.36E+3nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170322(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  6.37E+3nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153757(1-(2-Hydroxy-3-propyl-4-{4-[4-(1H-tetrazol-5-yl)-p...)
Affinity DataEC50:  348nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170321(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  779nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170320(1-Isopropyl-4-propyl-5-{4-[4-(1H-tetrazol-5-yl)-ph...)
Affinity DataEC50:  1.13E+3nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170306(1-(2,2-Dimethyl-propyl)-4-propyl-5-[4'-(1H-tetrazo...)
Affinity DataEC50:  318nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170319(1-Pentyl-4-propyl-5-{4-[4-(1H-tetrazol-5-yl)-pheno...)
Affinity DataEC50:  598nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170316(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  879nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170317(1-(2,2-Dimethyl-propyl)-4-propyl-5-{3-[4-(1H-tetra...)
Affinity DataEC50:  451nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170315(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  1.17E+3nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170314(1-(2,2-Dimethyl-propyl)-4-methyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  1.07E+3nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170313(4-Bromo-1-(2,2-dimethyl-propyl)-5-{4-[4-(1H-tetraz...)
Affinity DataEC50:  2.26E+3nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170311(1,4-Dipropyl-5-{4-[4-(1H-tetrazol-5-yl)-phenoxy]-b...)
Affinity DataEC50:  652nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170312(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  936nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 expressed in HEK293 cells done for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170310(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  984nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170309(1-(2,2-Dimethyl-propyl)-4-propyl-5-[3-(1H-tetrazol...)
Affinity DataEC50:  134nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170308(1-(2,2-Dimethyl-propyl)-5-{4-[4-(1H-tetrazol-5-yl)...)
Affinity DataEC50:  3.59E+3nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170307(3-(2,2-Dimethyl-propyl)-7-propyl-6-{4-[4-(1H-tetra...)
Affinity DataEC50:  788nMAssay Description:Effective concentration for stimulation of [35S]GTP-gamma-S, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed