Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 1587
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12396(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  0.0700nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12389(1-[5-(5-Chloro-thiophen-2-yl)-isoxazol-3-ylmethyl]...)
Affinity DataKi:  0.100nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12387(1-[5-(5-Chloro-thiophen-2-yl)-isoxazol-3-ylmethyl]...)
Affinity DataKi:  0.25nM ΔG°:  -54.8kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12395(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  0.300nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12384(7-Chloro-1-[5-(5-chloro-thiophen-2-yl)-isoxazol-3-...)
Affinity DataKi:  0.700nM ΔG°:  -52.3kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12381(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  1nM ΔG°:  -51.4kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12388(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  1nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12392(3-bromo-1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3...)
Affinity DataKi:  2nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12379(1-[5-(5-Chloro-thiophen-2-yl)-isoxazol-3-ylmethyl]...)
Affinity DataKi:  2nM ΔG°:  -49.7kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12391(3-chloro-1-{[5-(5-chlorothien-2-yl)isoxazol-3-yl]m...)
Affinity DataKi:  2nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12390(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  2nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12374(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12400(1-{[(4-chlorophenyl)carbamoyl]methyl}-N-[1-(propan...)
Affinity DataKi:  3nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12393(1-[5-(5-Chlorothiophen-2-yl)isoxazol-3-ylmethyl]-3...)
Affinity DataKi:  3nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12385(1-[5-(5-Chloro-thiophen-2-yl)-isoxazol-3-ylmethyl]...)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12372(2-carboxyindole-based inhibitor 10 | 2-carboxyindo...)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12375(5-chloro-1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-...)
Affinity DataKi:  5nM ΔG°:  -47.4kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12383(6-Chloro-1-[5-(5-chloro-thiophen-2-yl)-isoxazol-3-...)
Affinity DataKi:  7nM ΔG°:  -46.5kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12382(4-Chloro-1-[5-(5-chloro-thiophen-2-yl)-isoxazol-3-...)
Affinity DataKi:  7nM ΔG°:  -46.5kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12397(1-[5-(5-Chloro-thiophen-2-yl)-isoxazol-3-ylmethyl]...)
Affinity DataKi:  7nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12378(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  9nM ΔG°:  -45.9kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12376(5-bromo-1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3...)
Affinity DataKi:  9nM ΔG°:  -45.9kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12386(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  18nM ΔG°:  -44.2kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12380(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  20nM ΔG°:  -43.9kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12402(1-[(3-carbamimidoylphenyl)methyl]-N-[(3,5-dichloro...)
Affinity DataKi:  25nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12401(1-{[(4-chlorophenyl)carbamoyl]methyl}-3-cyano-7-me...)
Affinity DataKi:  26nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12394(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]meth...)
Affinity DataKi:  55nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12398(1-[(3-methoxyphenyl)methyl]-N-[1-(propan-2-yl)pipe...)
Affinity DataKi:  89nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12399(3-Cyano-1-(3-methoxy-benzyl)-7-methyl-1H-indole-2-...)
Affinity DataKi:  406nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12377(5-(benzyloxy)-1-{[5-(5-chlorothiophen-2-yl)-1,2-ox...)
Affinity DataKi:  835nM ΔG°:  -34.7kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed