Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 1911
TargetInsulin receptor(Human)
Merck Research Laboratories

LigandPNGBDBM2580(methyl (15R,16S,18S)-16-hydroxy-15-methyl-3-oxo-28...)
Affinity DataIC50: 210nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Merck Research Laboratories

LigandPNGBDBM2580(methyl (15R,16S,18S)-16-hydroxy-15-methyl-3-oxo-28...)
Affinity DataIC50: 470nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15015(2-tert-Butyl 4-Ethyl 3-Ethyl-5-formyl-1H-pyrrole-2...)
Affinity DataIC50: 490nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15012(2,4-diethyl 3-ethyl-5-formyl-1H-pyrrole-2,4-dicarb...)
Affinity DataIC50: 1.10E+3nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15015(2-tert-Butyl 4-Ethyl 3-Ethyl-5-formyl-1H-pyrrole-2...)
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15016(ethyl 5-(tert-butylcarbamoyl)-4-ethyl-2-formyl-1H-...)
Affinity DataIC50: 2.60E+3nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15011(2,4-diethyl 5-formyl-3-methyl-1H-pyrrole-2,4-dicar...)
Affinity DataIC50: 2.70E+3nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15017(2-tert-Butyl 4-Ethyl 3-Ethyl-5-formyl-1-methyl-1H-...)
Affinity DataIC50: 4.30E+3nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15012(2,4-diethyl 3-ethyl-5-formyl-1H-pyrrole-2,4-dicarb...)
Affinity DataIC50: 5.40E+3nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15011(2,4-diethyl 5-formyl-3-methyl-1H-pyrrole-2,4-dicar...)
Affinity DataIC50: 1.20E+4nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15017(2-tert-Butyl 4-Ethyl 3-Ethyl-5-formyl-1-methyl-1H-...)
Affinity DataIC50: 1.20E+4nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15016(ethyl 5-(tert-butylcarbamoyl)-4-ethyl-2-formyl-1H-...)
Affinity DataIC50: 1.70E+4nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15013(2,4-diethyl 5-(hydroxymethyl)-3-methyl-1H-pyrrole-...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15014(N,N,N,N-Tetraethyl-5-formyl-3-methyl-1H-pyrrole-2,...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15013(2,4-diethyl 5-(hydroxymethyl)-3-methyl-1H-pyrrole-...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15014(N,N,N,N-Tetraethyl-5-formyl-3-methyl-1H-pyrrole-2,...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed