Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 1398
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11258(ethyl (2E,4S)-4-[(2S)-2-[(2S)-2-{[(benzyloxy)carbo...)
Affinity DataIC50: 1.10E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11256(ethyl (2E,4S)-4-[(2S)-2-[(2S)-2-{[(benzyloxy)carbo...)
Affinity DataIC50: 1.10E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11253(ethyl (2E,4S)-4-[(2R,5S)-2-benzyl-6-methyl-5-[(5-m...)
Affinity DataIC50: 1.30E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11255(ethyl (2E,4S)-4-[(2S)-3-(4-fluorophenyl)-2-[(2S)-3...)
Affinity DataIC50: 2.10E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11257(ethyl (2E,4S)-4-[(2S)-2-[(2S)-3-methyl-2-[(5-methy...)
Affinity DataIC50: 3.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11252(ethyl (2E,4S)-4-[(2R,5S)-5-{[(benzyloxy)carbonyl]a...)
Affinity DataIC50: 3.10E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11254(ethyl (2E,4S)-4-[(2R,5S)-2-benzyl-5-{[(benzyloxy)c...)
Affinity DataIC50: 3.80E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11251(ethyl (2E,4S)-4-[(2R,5S)-2-[(4-fluorophenyl)methyl...)
Affinity DataIC50: 3.90E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11249(ethyl (2E,4S)-4-[(2S)-2-[(2S)-3-methyl-2-[(5-methy...)
Affinity DataIC50: 8.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11230(ethyl (2E,4S)-4-[(2S)-2-[(2S)-2-{[(benzyloxy)carbo...)
Affinity DataIC50: 8.50E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11244(ethyl (2E,4S)-4-[(2R,5S)-5-{[(benzyloxy)carbonyl]a...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11248(ethyl (2E,4S)-4-[(2S)-2-[(2S)-2-{[(benzyloxy)carbo...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11229(AG7088 analogue 2a | CHEMBL20636 | N-[(5-methyliso...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11246(ethyl (2E,4S)-4-[(2R,5S)-2-benzyl-5-{[(benzyloxy)c...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11245(CHEMBL194398 | ethyl (2E,4S)-4-[(2R,5S)-2-benzyl-6...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11243(ethyl (2E,4S)-4-[((2R,5S)-2-(4-fluorobenzyl)-6-met...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11261(ethyl (2E,4S)-4-[(2S)-2-[(2E)-3-[4-(dimethylamino)...)
Affinity DataKi:  520nM ΔG°:  -35.9kJ/mole IC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11260(ethyl (2E,4S)-4-[(2S)-2-[(2E)-3-(4-nitrophenyl)pro...)
Affinity DataKi:  2.48E+3nM ΔG°:  -32.0kJ/mole IC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11263(ethyl (2E,4S)-4-[(2S)-2-[(2E)-3-(2H-1,3-benzodioxo...)
Affinity DataKi:  3.05E+3nM ΔG°:  -31.5kJ/mole IC50: 7.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11259(ethyl (2E,4S)-5-phenyl-4-[(2S)-3-phenyl-2-[(2E)-3-...)
Affinity DataKi:  6.44E+3nM ΔG°:  -29.6kJ/mole IC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11262(ethyl (2E,4S)-4-({N-[(2E)-3-(2,4-dimethoxyphenyl)p...)
Affinity DataKi:  9.05E+3nM ΔG°:  -28.8kJ/mole IC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed