Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50016503
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50148291(((S)-1-Formyl-pentyl)-carbamic acid (S)-2-cyclohex...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169767(ethyl 2-((S)-2-(((S)-1-cyclohexylpropan-2-yloxy)ca...)
Affinity DataIC50: 230nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169766([(S)-1-(Thiophene-2-carbonyl)-pentyl]-carbamic aci...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169769((S)-1-cyclohexylpropan-2-yl (S)-1-oxo-1-(thiazol-2...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169770((S)-1-cyclohexylpropan-2-yl (S)-1-oxo-1-(5-phenyl-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169762([(S)-1-(4-Phenyl-thiazole-2-carbonyl)-pentyl]-carb...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169765([(S)-1-(5-Methyl-[1,2,4]oxadiazole-3-carbonyl)-pen...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169763(2-[2-(2-Propoxy-benzoylamino)-acetyl]-thiazole-4-c...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169764([(S)-1-(4-Trifluoromethyl-thiazole-2-carbonyl)-pen...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169768(2-[(S)-2-((S)-2-Benzyloxycarbonylamino-4-methyl-pe...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169771(2-[(S)-2-(1-Benzyl-propoxycarbonylamino)-hexanoyl]...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed