Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50000489
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50004413(CHEMBL433291 | tert-butyl 3-[1-(1-cyclohexylmethyl...)
Affinity DataIC50: 31nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006421(CHEMBL67542 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50: 32nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006418(CHEMBL67431 | {1-[1-(1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50: 33nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006440({1-[1-(1-Cyclohexylmethyl-2-hydroxy-3-{1-[2-(1-oxy...)
Affinity DataIC50: 37nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006438(CHEMBL305761 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50: 39nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006431(CHEMBL304121 | {1-[1-{1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50: 39nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006429({1-[1-{1-Cyclohexylmethyl-2-hydroxy-3-[4-(2-pyridi...)
Affinity DataIC50: 41nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006436(CHEMBL66684 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50: 81nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006433(CHEMBL406475 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50: 124nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006430(CHEMBL65206 | {1-[1-{1-Cyclohexylmethyl-3-[1-(2-di...)
Affinity DataIC50: 145nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006425(CHEMBL303322 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50: 198nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006437({1-[1-[3-(4-Allyl-5-trifluoromethyl-4H-[1,2,4]tria...)
Affinity DataIC50: 206nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006419(CHEMBL291671 | (5-{3-[2-(2-tert-Butoxycarbonylamin...)
Affinity DataIC50: 207nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006427(CHEMBL68229 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50: 240nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006422(CHEMBL309127 | {1-[1-(1-Cyclohexylmethyl-3-cyclohe...)
Affinity DataIC50: 289nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006428({1-[1-(1-Cyclohexylmethyl-2-hydroxy-3-{1-[(2-morph...)
Affinity DataIC50: 314nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006439({1-[1-(1-Cyclohexylmethyl-2-hydroxy-3-{1-[2-(4-met...)
Affinity DataIC50: 359nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006424({1-[1-[1-Cyclohexylmethyl-2-hydroxy-3-(2-methyl-5-...)
Affinity DataIC50: 392nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006435(CHEMBL67827 | (5-{3-[2-(2-tert-Butoxycarbonylamino...)
Affinity DataIC50: 396nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006432(CHEMBL308658 | {1-[1-[3-(1-Carbamoylmethyl-1H-tetr...)
Affinity DataIC50: 448nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006434(CHEMBL63190 | 4-[2-(5-{3-[2-(2-tert-Butoxycarbonyl...)
Affinity DataIC50: 678nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006420(CHEMBL63826 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50: 708nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006423({1-[1-(1-Cyclohexylmethyl-3-{1-[(2-dimethylamino-e...)
Affinity DataIC50: 1.29E+3nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006426(CHEMBL302255 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50: 3.31E+3nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed