Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50039277
TargetMitogen-activated protein kinase 14(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK3(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataKi:  1nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50208517(KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of ATMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase Lck(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50129307(2-(3-tert-Butyl-ureido)-benzothiazole-6-carboxylic...)
Affinity DataKi:  4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50325991(CHEMBL1242100 | CHEMBL541400 | CHEMBL1190711 | 2-(...)
Affinity DataKi:  7.5nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataKi:  14nMAssay Description:Inhibition of Bcr-AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50186460(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-...)
Affinity DataKi:  16nMAssay Description:Inhibition of ITKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)
Affinity DataKi:  20nMAssay Description:Inhibition of p110deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataKi:  22nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM25919(N-(2-aminoethyl)-3,12-dimethyl-2,5,8-triazatricycl...)
Affinity DataKi:  300nMAssay Description:Inhibition of IKK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM15160(CHEMBL362016 | 1-[1-({4-[6-(2-methylpropyl)-5-oxo-...)
Affinity DataKi:  325nMAssay Description:Inhibition of Akt2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM15152(1-(1-{[4-(6-methyl-5-oxo-3-phenyl-4,5-dihydropyraz...)
Affinity DataKi:  760nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed