Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 1196
TargetAromatase(Human)
Ohio State University

LigandChemical structure of BindingDB Monomer ID 9893BDBM9893(7-(benzyloxy)-2-(1H-imidazol-1-yl)-3-phenyl-4H-chr...)
Affinity DataKi:  250nM ΔG°:  -39.2kJ/mole IC50: 520nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandChemical structure of BindingDB Monomer ID 9891BDBM9891(2-(1H-Imidazol-1-yl)-7-methoxy-3-phenyl-4H-1-benzo...)
Affinity DataKi:  680nM ΔG°:  -36.6kJ/mole IC50: 770nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandChemical structure of BindingDB Monomer ID 9460BDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataKi:  1.41E+3nM ΔG°:  -34.7kJ/mole IC50: 2.80E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandChemical structure of BindingDB Monomer ID 9892BDBM9892(2-(1H-imidazol-1-yl)-7-methoxy-3-(4-methoxyphenyl)...)
Affinity DataKi:  1.82E+3nM ΔG°:  -34.1kJ/mole IC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandChemical structure of BindingDB Monomer ID 9894BDBM9894(CHEMBL189274 | 2-(1H-Imidazol-1-yl)-3-(4-methoxyph...)
Affinity DataKi:  4.40E+3nM ΔG°:  -31.8kJ/mole IC50: 4.70E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandChemical structure of BindingDB Monomer ID 9461BDBM9461(5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataKi:  1.20E+4nM ΔG°:  -29.2kJ/mole IC50: 3.40E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandChemical structure of BindingDB Monomer ID 9895BDBM9895(CHEMBL190099 | 7-methoxy-3-phenyl-2-(1H-1,2,4-tria...)
Affinity DataIC50: 1.80E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandChemical structure of BindingDB Monomer ID 9896BDBM9896(2-(1H-imidazol-2-ylsulfanyl)-7-methoxy-3-phenyl-4H...)
Affinity DataIC50: 5.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandChemical structure of BindingDB Monomer ID 9897BDBM9897(7-Methoxy-2-(1-methyl-1H-imidazolyl-2-thio)-3-phen...)
Affinity DataIC50: 5.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandChemical structure of BindingDB Monomer ID 9898BDBM9898(7-Methoxy-3-phenyl-2-(1H-1,2,4-triazolyl-3-thio)-4...)
Affinity DataIC50: 5.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed