Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50016311
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167611((2R,5R)-1-[4-(2-Chloro-4-fluoro-benzyloxy)-benzene...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167619((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(4-methyl-benz...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167618((2R,5R)-1-[4-(4-Bromo-benzyloxy)-benzenesulfonyl]-...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167620((2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 2.10nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167621((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(3-methyl-benz...)
Affinity DataIC50: 2.80nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167609((2R,5R)-1-[4-(2,4-Dichloro-benzyloxy)-benzenesulfo...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167605((2R,5R)-1-[4-(4-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 3.5nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167617((2R,5R)-1-[4-(3-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 4.30nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167605((2R,5R)-1-[4-(4-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 5.20nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167620((2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 6.20nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167608((2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 6.5nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167606((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(2-methyl-pyri...)
Affinity DataIC50: 6.70nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167610((2R,5R)-1-[4-(2-Ethyl-benzyloxy)-benzenesulfonyl]-...)
Affinity DataIC50: 6.70nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167613((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(2-methyl-benz...)
Affinity DataIC50: 7.30nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167608((2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 7.30nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167607((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(quinolin-4-yl...)
Affinity DataIC50: 7.80nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167622((2R,5R)-1-[4-(2-Bromo-benzyloxy)-benzenesulfonyl]-...)
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167614((2R,5R)-5-Hydroxy-1-[4-(isoquinolin-1-ylmethoxy)-b...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167618((2R,5R)-1-[4-(4-Bromo-benzyloxy)-benzenesulfonyl]-...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167619((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(4-methyl-benz...)
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167622((2R,5R)-1-[4-(2-Bromo-benzyloxy)-benzenesulfonyl]-...)
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167621((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(3-methyl-benz...)
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167623((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(3-methyl-isot...)
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167612((2R,5R)-5-Hydroxy-1-[4-(2-isopropyl-benzyloxy)-ben...)
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167613((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(2-methyl-benz...)
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167624((2R,5R)-1-[4-(3-Bromo-benzyloxy)-benzenesulfonyl]-...)
Affinity DataIC50: 15nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167616((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(4-methyl-isot...)
Affinity DataIC50: 16nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167617((2R,5R)-1-[4-(3-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167615((2R,5R)-1-[4-(3-Chloro-pyridin-4-ylmethoxy)-benzen...)
Affinity DataIC50: 19nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167609((2R,5R)-1-[4-(2,4-Dichloro-benzyloxy)-benzenesulfo...)
Affinity DataIC50: 19nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167610((2R,5R)-1-[4-(2-Ethyl-benzyloxy)-benzenesulfonyl]-...)
Affinity DataIC50: 36nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167614((2R,5R)-5-Hydroxy-1-[4-(isoquinolin-1-ylmethoxy)-b...)
Affinity DataIC50: 53nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167618((2R,5R)-1-[4-(4-Bromo-benzyloxy)-benzenesulfonyl]-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167607((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(quinolin-4-yl...)
Affinity DataIC50: 170nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167612((2R,5R)-5-Hydroxy-1-[4-(2-isopropyl-benzyloxy)-ben...)
Affinity DataIC50: 188nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167619((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(4-methyl-benz...)
Affinity DataIC50: 198nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167605((2R,5R)-1-[4-(4-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 255nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167614((2R,5R)-5-Hydroxy-1-[4-(isoquinolin-1-ylmethoxy)-b...)
Affinity DataIC50: 290nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167609((2R,5R)-1-[4-(2,4-Dichloro-benzyloxy)-benzenesulfo...)
Affinity DataIC50: 430nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167611((2R,5R)-1-[4-(2-Chloro-4-fluoro-benzyloxy)-benzene...)
Affinity DataIC50: 592nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167617((2R,5R)-1-[4-(3-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 679nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167613((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(2-methyl-benz...)
Affinity DataIC50: 690nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167622((2R,5R)-1-[4-(2-Bromo-benzyloxy)-benzenesulfonyl]-...)
Affinity DataIC50: 715nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167621((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(3-methyl-benz...)
Affinity DataIC50: 773nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167608((2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 790nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167615((2R,5R)-1-[4-(3-Chloro-pyridin-4-ylmethoxy)-benzen...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167610((2R,5R)-1-[4-(2-Ethyl-benzyloxy)-benzenesulfonyl]-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167612((2R,5R)-5-Hydroxy-1-[4-(2-isopropyl-benzyloxy)-ben...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167620((2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed