Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50016204
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166296((S)-2-{3-[1-(6-Methoxy-quinolin-3-yl)-2-methyl-5-t...)
Affinity DataEC50:  49nMAssay Description:Maximal intrinsic response against peroxisome proliferator activated receptor gamma transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166298((S)-2-{4-Chloro-3-[1-(6-chloro-benzo[d]isoxazol-3-...)
Affinity DataEC50:  3nMAssay Description:Maximal intrinsic response against peroxisome proliferator activated receptor gamma transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166300((S)-2-{2-Chloro-5-[1-(6-chloro-benzo[d]isoxazol-3-...)
Affinity DataEC50:  3nMAssay Description:Maximal intrinsic response against peroxisome proliferator activated receptor gamma transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166302((S)-2-{5-[1-(6-Chloro-benzo[d]isoxazol-3-yl)-2-met...)
Affinity DataEC50:  39nMAssay Description:Maximal intrinsic response against peroxisome proliferator activated receptor gamma transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166294((S)-2-{3-Chloro-5-[1-(6-chloro-benzo[d]isoxazol-3-...)
Affinity DataEC50:  114nMAssay Description:Maximal intrinsic response against peroxisome proliferator activated receptor gamma transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166301((4-Methoxy-phenyl)-[2-methyl-3-(3-prop-2-ynyloxy-b...)
Affinity DataEC50:  31nMAssay Description:Maximal intrinsic response against peroxisome proliferator activated receptor gamma transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166303({3-[1-(4-Methoxy-benzoyl)-2-methyl-5-trifluorometh...)
Affinity DataEC50:  16nMAssay Description:Maximal intrinsic response against peroxisome proliferator activated receptor gamma transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166293((S)-2-{3-[1-(6-Chloro-benzo[d]isoxazol-3-yl)-2-met...)
Affinity DataEC50:  195nMAssay Description:Maximal intrinsic response against peroxisome proliferator activated receptor gamma transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166291(3-Methyl-5-{4-[2-(methyl-pyridin-2-yl-amino)-ethox...)
Affinity DataEC50: >3.00E+3nMAssay Description:Maximal intrinsic response against peroxisome proliferator activated receptor gamma transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157917((S)-2-{3-[1-(4-Methoxy-benzoyl)-2-methyl-5-trifluo...)
Affinity DataEC50:  1nMAssay Description:Maximal intrinsic response against peroxisome proliferator activated receptor gamma transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166292((S)-2-{3-[1-(4-Methoxy-phenyl)-2-methyl-5-trifluor...)
Affinity DataEC50:  3nMAssay Description:Maximal intrinsic response against peroxisome proliferator activated receptor gamma transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166295((R)-2-{4-Chloro-3-[1-(6-methoxy-benzo[d]isoxazol-3...)
Affinity DataEC50:  3nMAssay Description:Maximal intrinsic response against peroxisome proliferator activated receptor gamma transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataEC50:  20nMAssay Description:Maximal intrinsic response against peroxisome proliferator activated receptor gamma transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166292((S)-2-{3-[1-(4-Methoxy-phenyl)-2-methyl-5-trifluor...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166300((S)-2-{2-Chloro-5-[1-(6-chloro-benzo[d]isoxazol-3-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166295((R)-2-{4-Chloro-3-[1-(6-methoxy-benzo[d]isoxazol-3...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157917((S)-2-{3-[1-(4-Methoxy-benzoyl)-2-methyl-5-trifluo...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166298((S)-2-{4-Chloro-3-[1-(6-chloro-benzo[d]isoxazol-3-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166302((S)-2-{5-[1-(6-Chloro-benzo[d]isoxazol-3-yl)-2-met...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166296((S)-2-{3-[1-(6-Methoxy-quinolin-3-yl)-2-methyl-5-t...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166293((S)-2-{3-[1-(6-Chloro-benzo[d]isoxazol-3-yl)-2-met...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166303({3-[1-(4-Methoxy-benzoyl)-2-methyl-5-trifluorometh...)
Affinity DataIC50: 42nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166305((S)-2-[3-(2-Methyl-5-trifluoromethoxy-1H-indol-3-y...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against Cytochrome P450 2C9 in ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166301((4-Methoxy-phenyl)-[2-methyl-3-(3-prop-2-ynyloxy-b...)
Affinity DataIC50: 62nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166294((S)-2-{3-Chloro-5-[1-(6-chloro-benzo[d]isoxazol-3-...)
Affinity DataIC50: 109nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166297((S)-2-{3-[1-(6-Methoxy-quinolin-2-yl)-2-methyl-5-t...)
Affinity DataIC50: 135nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166299((S)-2-[3-(2-Methyl-1-pyridin-2-yl-5-trifluorometho...)
Affinity DataIC50: 466nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166304((S)-2-{3-[1-(6-Chloro-benzo[d]isoxazol-3-yl)-2-met...)
Affinity DataIC50: 641nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166291(3-Methyl-5-{4-[2-(methyl-pyridin-2-yl-amino)-ethox...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed