Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 905
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7111((2S)-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxo...)
Affinity DataIC50: 2nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7107(CHEMBL190446 | (2S)-N-(5-cyclopropyl-1H-pyrazol-3-...)
Affinity DataIC50: 2nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7114(N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxo-2,3-...)
Affinity DataIC50: 11nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7118(CHEMBL192042 | (2S)-N-(5-Cyclopropyl-1H-pyrazol-3-...)
Affinity DataIC50: 17nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7112(N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2,4-dioxoi...)
Affinity DataIC50: 17nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7120((2S)-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxo...)
Affinity DataIC50: 20nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7103(1-(4-{2-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]-1-m...)
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7101((2S)-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxo...)
Affinity DataIC50: 37nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7108(N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(naphthalen-2-...)
Affinity DataIC50: 37nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7115(N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[4-(5-oxo-4,5-...)
Affinity DataIC50: 73nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7109(N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2,5-dioxop...)
Affinity DataIC50: 77nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7098((2S)-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-phenylpro...)
Affinity DataIC50: 84nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7094(N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-fluoro-2-pheny...)
Affinity DataIC50: 99nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7113(N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2,5-dioxoi...)
Affinity DataIC50: 124nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7104(N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-methyl-5...)
Affinity DataIC50: 150nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7106((2R)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[4-(1-oxo...)
Affinity DataIC50: 170nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7105(N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxo-5-ph...)
Affinity DataIC50: 200nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7102(N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxopiper...)
Affinity DataIC50: 240nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7110(CHEMBL189047 | (2R)-N-(5-Cyclopropyl-1H-pyrazol-3-...)
Affinity DataIC50: 455nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7095((2S)-2-Amino-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-p...)
Affinity DataIC50: 960nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7116(2-[4-(3-Benzyl-2-oxoimidazolidin-1-yl)phenyl]-N-(5...)
Affinity DataIC50: 1.45E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7092(CHEMBL190154 | (2S)-N-(5-Cyclopropyl-1H-pyrazol-3-...)
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7100((2R)-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxo...)
Affinity DataIC50: 2.50E+3nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7119(CHEMBL192179 | (2R)-N-(5-Cyclopropyl-1H-pyrazol-3-...)
Affinity DataIC50: 2.50E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7097(N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-oxo-2-phenylac...)
Affinity DataIC50: 2.60E+3nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7099(CHEMBL365988 | (2R)-N-(5-Cyclopropyl-1H-pyrazol-3-...)
Affinity DataIC50: 6.00E+3nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7117(CHEMBL365355 | (2R)-N-(5-Cyclopropyl-1H-pyrazol-3-...)
Affinity DataIC50: 8.50E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7096(N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2,2-diphenylacet...)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM7093(CHEMBL370036 | (2R)-N-(5-Cyclopropyl-1H-pyrazol-3-...)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed