Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50016101
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165053(6-Furan-2-yl-9-naphthalen-2-ylmethyl-9H-purin-2-yl...)
Affinity DataKi:  1.40nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165064(9-(2-Fluoro-4-trifluoromethyl-benzyl)-6-furan-2-yl...)
Affinity DataKi:  2.80nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165063(9-(2-Benzenesulfonylmethyl-benzyl)-6-furan-2-yl-9H...)
Affinity DataKi:  3.10nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50048466(CHEMBL17127 | SCH58261 | 2-(furan-2-yl)-7-phenethy...)
Affinity DataKi:  4.30nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165069(9-(2,6-Difluoro-benzyl)-6-furan-2-yl-9H-purin-2-yl...)
Affinity DataKi:  4.5nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165067(6-Furan-2-yl-9-naphthalen-1-ylmethyl-9H-purin-2-yl...)
Affinity DataKi:  5.60nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165059(9-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-6-furan-2...)
Affinity DataKi:  6.30nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165052(6-Furan-2-yl-9-(3-phenyl-propyl)-9H-purin-2-ylamin...)
Affinity DataKi:  6.80nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165065(9-(2,6-Dichloro-benzyl)-6-furan-2-yl-9H-purin-2-yl...)
Affinity DataKi:  7.10nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165071(2-amino-6-(2-furyl)-9-(4-methoxyphenylmethyl)-9Hpu...)
Affinity DataKi:  7.70nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165070(9-(3-Fluoro-4-trifluoromethyl-benzyl)-6-furan-2-yl...)
Affinity DataKi:  8.70nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165061(6-Furan-2-yl-9-(4-isopropyl-benzyl)-9H-purin-2-yla...)
Affinity DataKi:  10nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165062(9-(3-methoxybenzyl)-6-(furan-2-yl)-9H-purin-2-amin...)
Affinity DataKi:  12.3nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165056(9-(4-(trifluoromethyl)benzyl)-6-(furan-2-yl)-9H-pu...)
Affinity DataKi:  20.5nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165058(9-(4-Chloro-benzyl)-6-furan-2-yl-9H-purin-2-ylamin...)
Affinity DataKi:  21.5nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165055(6-Furan-2-yl-9-(2-methoxy-benzyl)-9H-purin-2-ylami...)
Affinity DataKi:  22nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165057(6-Furan-2-yl-9-(2,4,6-trifluoro-benzyl)-9H-purin-2...)
Affinity DataKi:  26nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165066(9-benzyl-6-(furan-2-yl)-9H-purin-2-amine | 9-Benzy...)
Affinity DataKi:  34.9nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165054(6-Furan-2-yl-9-phenyl-9H-purin-2-ylamine | CHEMBL4...)
Affinity DataKi:  68.5nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165068(6-Furan-2-yl-9-phenethyl-9H-purin-2-ylamine | CHEM...)
Affinity DataKi:  271nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165060(6-Furan-2-yl-9-(1-phenyl-ethyl)-9H-purin-2-ylamine...)
Affinity DataKi:  381nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed