Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50016043
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164242(6-(5-Phenyl-2-piperidin-4-yl-3H-imidazol-4-yl)-1-(...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164228(1-(isopropylsulfonyl)-6-(4-phenyl-1H-imidazol-5-yl...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164240(6-[5-(4-Fluoro-phenyl)-3H-imidazol-4-yl]-1-(propan...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164236(CHEMBL404377 | CHEMBL363831 | 6-[2-tert-Butyl-5-(2...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164230(6-[5-(4-Fluoro-phenyl)-2-isopropyl-3H-imidazol-4-y...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164239(6-[2-Ethyl-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-1...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164229(6-[2-tert-Butyl-5-(2,4-difluoro-phenyl)-3H-imidazo...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164232(6-[2-(2,6-Difluoro-phenyl)-5-phenyl-3H-imidazol-4-...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164231(6-[2-(1-Isobutyl-piperidin-4-yl)-5-phenyl-3H-imida...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164232(6-[2-(2,6-Difluoro-phenyl)-5-phenyl-3H-imidazol-4-...)
Affinity DataIC50: 6.30nMAssay Description:In vitro inhibitory concentration against Cytochrome P450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164233(6-[2-(2,6-Dichloro-phenyl)-5-phenyl-3H-imidazol-4-...)
Affinity DataIC50: 15.3nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164235(6-[2-tert-Butyl-5-(4-fluoro-phenyl)-3H-imidazol-4-...)
Affinity DataIC50: 15.9nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164234(1-Cyclopentanesulfonyl-6-[2-(2,6-difluoro-phenyl)-...)
Affinity DataIC50: 19.9nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164238(6-[5-(4-Fluoro-phenyl)-3-methyl-3H-imidazol-4-yl]-...)
Affinity DataIC50: 20.7nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164237(2-Amino-6-[2-(2,6-difluoro-phenyl)-5-phenyl-3H-imi...)
Affinity DataIC50: 22.8nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164241(6-[5-(4-Fluoro-phenyl)-3-piperidin-4-yl-3H-imidazo...)
Affinity DataIC50: 125nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164240(6-[5-(4-Fluoro-phenyl)-3H-imidazol-4-yl]-1-(propan...)
Affinity DataIC50: 800nMAssay Description:In vitro inhibitory concentration against Cytochrome P450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164228(1-(isopropylsulfonyl)-6-(4-phenyl-1H-imidazol-5-yl...)
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro inhibitory concentration against Cytochrome P450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164239(6-[2-Ethyl-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-1...)
Affinity DataIC50: 4.40E+3nMAssay Description:In vitro inhibitory concentration against Cytochrome P450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164231(6-[2-(1-Isobutyl-piperidin-4-yl)-5-phenyl-3H-imida...)
Affinity DataIC50: 5.30E+3nMAssay Description:In vitro inhibitory concentration against Cytochrome P450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164230(6-[5-(4-Fluoro-phenyl)-2-isopropyl-3H-imidazol-4-y...)
Affinity DataIC50: 6.10E+3nMAssay Description:In vitro inhibitory concentration against Cytochrome P450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164234(1-Cyclopentanesulfonyl-6-[2-(2,6-difluoro-phenyl)-...)
Affinity DataIC50: 1.30E+4nMAssay Description:In vitro inhibitory concentration against Cytochrome P450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164235(6-[2-tert-Butyl-5-(4-fluoro-phenyl)-3H-imidazol-4-...)
Affinity DataIC50: 3.18E+4nMAssay Description:In vitro inhibitory concentration against Cytochrome P450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed