Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50000452
TargetMuscarinic acetylcholine receptor M1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005850((2'S)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,4...)
Affinity DataKi:  2.90E+3nMAssay Description:Compound was evaluated for its binding affinity against Muscarinic acetylcholine receptor M1 in guinea pig cerebral cortex using (-)-[3H]-QNB as radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005844(CHEMBL289894 | (2S,5'R)-5'-methyldihydrospiro[4-az...)
Affinity DataKi:  6.30E+3nMAssay Description:Compound was evaluated for its binding affinity against Muscarinic acetylcholine receptor M1 in guinea pig cerebral cortex using (-)-[3H]-QNB as radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005848((2'S)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,4...)
Affinity DataKi:  6.30E+3nMAssay Description:Compound was evaluated for its binding affinity against Muscarinic acetylcholine receptor M1 in guinea pig cerebral cortex using (-)-[3H]-QNB as radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005845(CHEMBL38423 | (2S,5'S)-5'-methyldihydrospiro[4-aza...)
Affinity DataKi:  6.50E+3nMAssay Description:Compound was evaluated for its binding affinity against Muscarinic acetylcholine receptor M1 in guinea pig cerebral cortex using (-)-[3H]-QNB as radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005846(CHEMBL39922 | 2',2'-dimethylspiro[4-azabicyclo[2.2...)
Affinity DataKi:  9.30E+3nMAssay Description:Compound was evaluated for its binding affinity against Muscarinic acetylcholine receptor M1 in guinea pig cerebral cortex using (-)-[3H]-QNB as radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005850((2'S)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,4...)
Affinity DataKi:  9.70E+3nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M2 in guinea pig heart using (-)-[3H]-QNB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor(Guinea pig)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005850((2'S)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,4...)
Affinity DataKi:  1.50E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M3 in guinea pig parotid gland using (-)-[3H]-QNB as radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005847(CHEMBL287834 | (2R,5'S)-5'-methyldihydro-3'H-spiro...)
Affinity DataKi:  1.50E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M2 in guinea pig heart using (-)-[3H]-QNB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005847(CHEMBL287834 | (2R,5'S)-5'-methyldihydro-3'H-spiro...)
Affinity DataKi:  1.50E+4nMAssay Description:Compound was evaluated for its binding affinity against Muscarinic acetylcholine receptor M1 in guinea pig cerebral cortex using (-)-[3H]-QNB as radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005849(CHEMBL290715 | spiro[4-azabicyclo[2.2.2]octane-2,4...)
Affinity DataKi:  1.90E+4nMAssay Description:Compound was evaluated for its binding affinity against Muscarinic acetylcholine receptor M1 in guinea pig cerebral cortex using (-)-[3H]-QNB as radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005845(CHEMBL38423 | (2S,5'S)-5'-methyldihydrospiro[4-aza...)
Affinity DataKi: >2.00E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M2 in guinea pig heart using (-)-[3H]-QNB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005843(CHEMBL39843 | (2R,5'R)-5'-methyldihydro-3'H-spiro[...)
Affinity DataKi:  2.00E+4nMAssay Description:Compound was evaluated for its binding affinity against Muscarinic acetylcholine receptor M1 in guinea pig cerebral cortex using (-)-[3H]-QNB as radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005844(CHEMBL289894 | (2S,5'R)-5'-methyldihydrospiro[4-az...)
Affinity DataKi: >2.00E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M2 in guinea pig heart using (-)-[3H]-QNB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005848((2'S)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,4...)
Affinity DataKi: >2.10E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M2 in guinea pig heart using (-)-[3H]-QNB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005843(CHEMBL39843 | (2R,5'R)-5'-methyldihydro-3'H-spiro[...)
Affinity DataKi: >2.50E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M2 in guinea pig heart using (-)-[3H]-QNB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor(Guinea pig)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005848((2'S)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,4...)
Affinity DataKi:  2.50E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M3 in guinea pig parotid gland using (-)-[3H]-QNB as radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor(Guinea pig)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005845(CHEMBL38423 | (2S,5'S)-5'-methyldihydrospiro[4-aza...)
Affinity DataKi:  2.60E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M3 n guinea pig parotid gland using (-)-[3H]-QNB as radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005846(CHEMBL39922 | 2',2'-dimethylspiro[4-azabicyclo[2.2...)
Affinity DataKi:  3.00E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M2 in guinea pig heart using (-)-[3H]-QNB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor(Guinea pig)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005844(CHEMBL289894 | (2S,5'R)-5'-methyldihydrospiro[4-az...)
Affinity DataKi:  3.30E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M3 in guinea pig parotid gland using (-)-[3H]-QNB as radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor(Guinea pig)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005847(CHEMBL287834 | (2R,5'S)-5'-methyldihydro-3'H-spiro...)
Affinity DataKi:  3.50E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M3 in guinea pig parotid gland using (-)-[3H]-QNB as radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor(Guinea pig)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005846(CHEMBL39922 | 2',2'-dimethylspiro[4-azabicyclo[2.2...)
Affinity DataKi:  3.90E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M3 n guinea pig parotid gland using (-)-[3H]-QNB as radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005849(CHEMBL290715 | spiro[4-azabicyclo[2.2.2]octane-2,4...)
Affinity DataKi:  5.00E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M2 in guinea pig heart using (-)-[3H]-QNB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor(Guinea pig)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005843(CHEMBL39843 | (2R,5'R)-5'-methyldihydro-3'H-spiro[...)
Affinity DataKi:  7.80E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M3 n guinea pig parotid gland using (-)-[3H]-QNB as radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor(Guinea pig)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005849(CHEMBL290715 | spiro[4-azabicyclo[2.2.2]octane-2,4...)
Affinity DataKi:  8.60E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M3 in guinea pig parotid gland using (-)-[3H]-QNB as radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed